Switches (bistability) and oscillations (limit cycle) are omnipresent in biological networks. Synthetic genetic networks producing bistability and oscillations have been designed and constructed experimentally. However, in real biological systems, regulatory circuits are usually interconnected and the dynamics of those complex networks is often richer than the dynamics of simple modules. Here w...

Abstract We attempt to identify the driving region of combustion oscillations by methodologies based on symbolic dynamics, synchronization, and complex networks. As equivalence ratio is increased, dynamic behavior pressure fluctuations transitions from a stable state high-amplitude via type-II intermittent subsequent low-amplitude oscillations. Rayleigh index-based transition network entropy us...

We examine how the location of weak electrical coupling affects phase-locking in a pair of model fast-spiking interneurons. Each model neuron consists of a somatic compartment and a passive dendritic compartment. At relatively low frequencies, the phase-locking structure for somatic and dendritic coupling is qualitatively the same: below a critical frequency, stable synchronous and anti-phase a...

Stem cells and their relationship with mature tissues are of increasing interest in the biomedical sciences, but the dynamics of stem cell/tissue interactions are not well understood. We give a generic stem cell/tissue model and examine the dynamics of a specific case of this, namely, a fourcompartment model of blood cell production and regulation. We apply the findings to cyclical neutropenia ...

We investigated the origin of spontaneous transient inward current (STIC) oscillations in descending vasa recta (DVR) pericytes. In cells clamped at -80 mV, angiotensin II (ANG II; 10 nmol/l) induced oscillations with mean amplitude and frequency of -65.5 pA and 1.2 Hz. Simultaneous recording of cytoplasmic calcium ([Ca(2+)](CYT)) and membrane current oscillations verified their synchrony and t...

The low frequency cerebral blood flow velocity (CBFV) oscillations in neonates are commonly attributed to an under-dampened immature linear type cerebral autoregulation, and the 'instability' is regarded as causative for peri-intraventricular haemorrhage/periventricular leukomalacia. In contrast, oscillations susceptible to frequency entrainment are a fundamental part of the stable function of ...

A simple technique for achieving wavelength tunable and amplitude-equilibrium dual-wavelength fiber laser source based on a dual-pass Raman/Brillouin amplification configuration is proposed and experimentally investigated. A stable room-temperature dual-wavelength lasing oscillations with average channel power of more than 1 mW and signal-to-noise ratio of more than 30 dB were obtained with onl...