The chemical stability of ceftriaxone for injection reconstituted with water was studied at different storage conditions by a validated stability-indicating ion-pair liquid chromatographic method. The study was performed on ceftriaxone for injection samples obtained from two pharmaceutical laboratories, at three different temperatures: 23 oC ± 2 oC, + 8 oC ± 1 oC and 20 oC ± 0.5 oC, over 26 day...

a simple and reliable stability-indicating rp-hplc method was developed and validated for analysis of adefovir dipivoxil (adv).the chromatographic separation was performed on a c18 column using a mixture of acetonitrile-citrate buffer (10 mm at ph 5.2) 36:64 (%v/v) as mobile phase, at a flow rate of 1.5 ml/min. detection was carried out at 260 nm and a sharp peak was obtained for adv at a reten...