Gadolinium (Gd), an element that possesses a character similar to that of calcium or magnesium, is known to have a strong hemolytic effect on erythrocytes (RBC) at even very low concentrations. 3, 5 One of the major characteristics of sickle cell disease is hemolysis of the abnormal RBC. Therefore, concerns have been raised that Gadolinium, as an MRI contrast agent for clinical use, should not ...

OBJECTIVES Hemolysis of blood samples drawn in the emergency department (ED) is a common problem that can interfere with timely diagnosis and appropriate treatment. The objective of this study was to identify the smallest number of remediable factors that independently increases the risk of hemolysis to design an effective strategy to address this issue. METHODS This was a prospective, observ...

The practical importance for the pharmaceutical and cosmetics industries of the interactions between biological membranes and surfactant molecules has led to intensive research within this area. The interactions of non-ionic surfactant n-octyl-β-D-glucopyranoside (OG) with the human and rat erythrocyte membranes were studied. The in vitro hemolytic and antihemolytic activities were determined b...

The incidence and severity of chronic intravascular hemolysis was evaluated in a total of 41 patients following mitral valve replacement. Valve replacement was with a gamma-radiated frame-mounted aortic homograft in 21 patients and with a composite seat Starr-Edwards prosthesis, model 6310 or 6320, in 20 patients. The parameters used to assess hemolysis were hemoglobin, hematocrit, reticulocyte...