Over the past decade, the ideal model of shared decisionmaking has been increasingly promoted as the preferred standard of doctor-patient communication. The model stipulates that doctor and patient should be considered coequal discussion partners that negotiate their preferences to arrive at a shared treatment decision (Edwards and Elwyn 2009). Thereby, the model notably gives rise to the usage...

In this paper we analyze several semantic-aware Grid middleware services used in e-Science applications. We describe them according to a common analysis framework, so as to find their commonalities and their distinguishing features. As a result of this analysis we categorize these services into three groups: information services, data access services and decision support services. We make compa...

We propose that bio-inspired algorithms are best developed and analysed in the context of a multidisciplinary conceptual framework that provides for sophisticated biological models and well-founded analytical principles, and we outline such a framework here, in the context of AIS network models. We further propose ways to unify several domains into a common meta-framework, in the context of AIS...

If information systems (IS) are to yield real benefits for organisations, it is critical that they support the business goals of the enterprise and that they are successfully assimilated into routine use by organisational members. The conventional solutions to the achievement of strategic alignment and the management of change in IS development are typically top-down, relying in both areas on a...

SUPPLEMENTAL MATERIALS & METHODS: TABLE OF CONTENTS I. PRIMARY DATA GENERATION .........................................................................................3 Cell Culture and Cell Lines Assayed .....................................................................................................................................3 Sub-cellular Fractionation and RNA Isolation (CSHL)......

In this work, by replacing the traditional solid spokes with colloidal spokes, a vehicle wheel with a built-in suspension structure is proposed. Following the background and description of the wheel system, firstly, a vibration model of the wheel equipped with colloidal spokes is proposed, and based on such model the equivalent damping coefficients and spring constants are identified. Then, a m...

The Yoneda Lemma tells us that the Hom bifunctor is “non-degenerate” in a similar way. (a) For each object X ∈ C verify that hX := HomC(X,−) defines a functor C → Set. (b) Given two objects X,Y ∈ C state what it means to have hX ≈ hY as functors. (c) Given two objects X,Y ∈ C and an isomorphism of functors hX ≈ hY , prove that we have an isomorphism of objects X ≈ Y . [Hint: Let Φ : hX ∼ −→ hY ...

The contents of GABA, glutamine (Glu) and asparagine (Asp) acids as well as activities of glutamatdecarboxylase (GDK; CF 4.1.1.15) and 4-aminobutirat: 2-oxoglutarataminotransferase (GABA-T: CF 2.6.1.19) in brain cortex, cerebellum, brainstem and hypothalamus under impact of testosterone propionate at a dose of 5 mg/100 g of alive weight of adult albino male rats in spring and autumn were studie...

the present paper investigates the potential application of graphene sheets with attached nanoparticles as resonant sensors by introducing a nonlocal shear deformation plate model. to take into account an elastic connection between the nanoplate and the attached nanoparticle, the nanoparticle is considered as a mass-spring system. then, a combination of pseudo-spectral and integral quadrature m...

There are approximately 470,000 km(2) of karst aquifers that feed many large springs in North China. Turbulent flow often exists in these karst aquifers, which means that the classical ground water model based on Darcy's law cannot be applied here. Ground water data are rare for these aquifers. As a consequence, it is difficult to quantitatively investigate ground water flow in these karst syst...