T he antiphospholipid syndrome is an autoimmune disease, characterized by the presence of antiphospholipid antibodies, thromboses, repeat spontaneous abortions and thrombocytopenia. The syndrome may be encountered in patients without any clinical or laboratory indications of other systemic disease (primary), or may be encountered within the context of other systemic disease – more often with Sy...

Aims: Although the copper intrauterine device (Cu-IUD) is an effective contraceptive device, cases of pregnancy under Cu-IUD have been reported. We here report 10 women who got pregnant this condition, with special reference to etiologies and outcomes. Methodology: analyzed all at ATBEF Main Clinic from July 1, 2015 June 30, 2020. Results: retrieved patients. The durations use were 3 months 6 y...

Introduction: One factor known to cause thrombophilia in women with unexplained recurrent spontaneous abortion (RSA) is C677T polymorphism of methylenetetrahydrofolate reductase gene. This study aimed to determine the association between RSA and MTHFR C677T polymorphism in Iranian patients. Methods: In this case-control study, 30 patients with previous history of two or more consecutive unexpla...

Sir It has been estimated that 25-40% or more pregnancies end in spontaneous abortions and that at least 80% happened in the first trimester!. There are many causes of spontaneous abortion, but it is now known that about 60% of abortuses expelled spontaneously in the first trimester are chromosomally abnormaF. The types of chromosomal abnormality usually found in abortuses are autosomal trisomy...

The relation between anesthetic gas exposure and spontaneous abortion remains unresolved. We examined the effect of nitrous oxide on spontaneous abortion among female dental assistants. Questionnaires were sent to 7,000 dental assistants aged 18-39 years who were registered in California in 1987; 4,856 (69%) responded. Analysis was based on 1,465 respondents whose most recent pregnancy was conc...

Couples with multiple miscarriages are at risk for carrying a balanced translocation since they may produce unbalanced gametes. Chromosomal imbalances may lead to spontaneous abortions, or an offspring with multiple congenital anomalies. This report emphasizes the importance of the cytogenetic investigations in couples with recurrent spontaneous abortions. A couple was referred for cytogenetic ...