Spindle cell proliferations of diverse types which vary greatly in their behavior may occur in the urinary bladder. Some of them such as the inflammatory pseudotumor and the postoperative spindle cell nodule are reactive and clinically benign although they may be responsible for significant symptoms. On the other hand, certain other lesions such as sarcomatoid carcinomas are typically highly ma...

background: there is a paucity of information about the oral pathology related articles published in a pathology journal. this study aimed to audit the oral pathology related articles published in iranian journal of pathology (iran j pathol)from 2006 to 2015. methods: bibliometric analysis of issues of iran j pathol from 2006 to 2015 was performed using web-based search.the articles published w...

Background: Spindle cell lipoma (SCL) is an uncommon subtype of lipomas. It usually occurs in the posterior side trunk such as neck, back and shoulders rarely touches extremities. Only four cases SCL knee no popliteal fossa have been reported literature. We present herein largest case to our knowledge. Case presentation: A 75-year-...

The histogenetic relationship amongst various dendritic cells of the dermis which may express markers including factor XIIIa (FXIIIa) or CD34 remains unclear. In this study we utilized a sensitive indirect immunoperoxidase staining technique to identify CD34 and FXIIIa, as well the monocyte/macrophage markers KP-1 and MAC 387 expression in a variety of cutaneous dermal tumors of mesenchymal ori...

Aneuploidy and chromosome instability (CIN) are hallmarks of the majority of solid tumors, but the relationship between them is not well understood. In this issue, Thompson and Compton (Thompson, S.L., and D.A. Compton. 2008. Examining the link between chromosomal instability and aneuploidy in human cells. J. Cell. Biol. 180:665-672) investigate the mechanism of CIN in cancer cells and find tha...

Benign esophageal tumors are uncommon, leiomyomas being the most frequent. However, esophageal schwannomas are exceedingly rare. We report here on two instances of large esophageal schwannomas treated by enucleation. A 63-year-old male and a 32-year-old female were referred to us for abnormal chest X-rays. Computed tomography of the chest documented sizeable growths in the upper thoracic esopha...

Desmoplastic melanoma (DM) is a type of spindle cell melanoma characterized by the absence of pigment. The clinical diagnosis of DM represents a challenge for the practitioner and the pathologists because it can mimic benign or malignant skin tumors and even inflammatory skin disorders. We here discuss a case of a patient presented with multiple nodular lesions of the lower extremity following ...

aggressive fibromatosis or desmoid tumors, histologically indicated by small bundles of spindle cells in a fibrous background, are uncommon benign tumors without metastasis. they are recurrent and aggressive and their recurrence and severity is exacerbated following surgical operation. based on previous reports, these tumors rarely present as intra-abdominal abscesses. herein, a 54-year-old wom...