BACKGROUND Germ cell tumors (GCTs) in children are rare neoplasms with diverse pathological findings according to the site and age of presentation. The most common symptoms in children with mediastinal GCTs, which are nonspecific, are dyspnea, chest pain, cough, hemoptysis, vena cava occlusion syndrome, and fatigue/weakness. Because of these nonspecific symptoms, it is difficult to suspect a me...

Tumors of the central nervous system are common in the pediatric population and constitute the second most prevalent tumor type in children. Within this group, spinal cord tumors are relatively rare and account for 1 to 10% of all pediatric central nervous system tumors. We describe a very rare case of an intradural extramedullary spinal cord tumor with a subcutaneous mass and discuss its clini...

A 36-year-old female patient presented with shoulder pain experienced over a period of one year and progressive weakness in both legs for one month. A magnetic resonance imaging scan revealed an intradural extramedullary (IDEM) fusiform mass about 9.8 cm in length, heterogeneously enhanced at the level of C6-T4 with spinal cord compression. At the time of surgery, the surgeon found an encapsula...

BACKGROUND Glioblastoma (GBM) is the most common primary intracranial tumor, but metastases are rarely reported. Previous reports have documented the occurrence of drop metastases to the spine. However, few of these reports have demonstrated the occurrence of spinal metastases after biopsy with stable intracranial disease. Here we present such a case. CASE DESCRIPTION We present a case of GBM...

Primary intramedullary spinal cord tumors are rare in domestic animals and extremely rare in cats [l, 51. This report concerns a primary intramedullary spinal cord tumor in a cat. An 1 1-year-old spayed female domestic shorthair cat was presented to the University of Minnesota Teaching Hospital in lateral recumbency with tetraparesis. All laboratory parameters (electroencephalogram, cerebrospin...

STUDY DESIGN To analyze the expression profile of tumor endothelial marker 7 (TEM7) in the spinal cord and dorsal root ganglion (DRG). PURPOSE To investigate the expression profile of TEM7 in the spinal cord and DRG of adult and developing rats. OVERVIEW OF LITERATURE Tumor endothelial marker 7 (TEM7) is a putative transmembrane protein that is highly expressed in the tumor endothelium and ...

Spinal schwannomas are benign tumors arising from spinal nerve root sheaths. These are the most common intradural extramedullary spinal tumors. Schwannomas are mostly solid or heterogeneous solid tumors. Cystic schwannomas are rare lesions. We present a 27-year-old woman with an intradural extramedullary cystic tumor in the lower thoracic region who complained of back pain and walking difficult...

Cryptococcus neoformans is a yeast that most commonly infects the central nervous system. Meningitis and meningoencephalitis are the most common presentations of cryptococcosis. Cryptococcoma, however, is a rare entity characterized by localized, solid, tumor-like masses that are usually found in the cerebral hemispheres or cerebellum, but are extremely rare in the spinal cord. We report a case...

Metastases to the spine resulting in spinal neuropathy occur commonly _ The vast majority involve the vertebrae and the epidural spaces. Intradural metastases, either extraor intra-medullary arising from a primary lesion outside of the central nervous system are seldom encountered. Another rare form of metastatic disease to the spinal central nervous system is leptomeningeal carcinomatosis. Thi...

Subacute necrotizing myelopathy (SNM) or Foix-Alajouanine syndrome is a rare disease characterized by progressive neurological dysfunction caused by a spinal dural arteriovenous fistula (AVF). Radiological diagnosis is usually suspected when there is intramedullary nonspecific enhancement and perimedullary flow voids. Ring-enhancement is rarely reported in the scope of AVF, which poses a diagno...