BACKGROUND Several studies have shown that muscarinic cholinergic agonists cause antinociception in humans and animals when given by both spinal and non-spinal parenteral routes. It is uncertain which subtype of muscarinic receptor is involved in spinally mediated antinociceptive effects caused by these drugs. The cholinergic receptor agonists McN-A-343 (M1 selective; 3.89 to 389 nmol) and carb...

BACKGROUND We aimed to investigate whether the addition of non-steroidal anti-inflammatory drugs or spinal manipulative therapy, or both, would result in faster recovery for patients with acute low back pain receiving recommended first-line care. METHODS 240 patients with acute low back pain who had seen their general practitioner and had been given advice and paracetamol were randomly alloca...

The brain-derived neurotrophic factor gene (BDNF) is one of many genes thought to influence neuronal survival, synaptic plasticity, and neurogenesis. A common single nucleotide polymorphism (SNP) of the BDNF gene due to valine-to-methionine substitution at codon 66 (BDNF Val66Met) in the normal population has been associated with complex neuronal phenotype, including differences in brain morpho...

Curve flexibility in adolescent idiopathic scoliosis (AIS) was one of the major concerns of spinal surgeons since the evolution of surgical correction techniques. In this respect, many tried to identify which criteria denote more rigid curve. In the present study, we aimed toward determining important factors influencing AIS curve flexibility on supine bending films. We assessed radiographs of ...

conclusions this study demonstrated that most victims of csfx in our region are 16 to 40 years of age. a male predominance was observed, and motor vehicle collisions were the most frequent trauma mechanism leading to cervical spine injury (mostly due to car rollover accidents), with falls as the second most frequent. the rate of sci in our study was 3.62% of all cases and the mortality rate was...

In this paper we present a Hough Transform-based method for the detection of the spinal district in X-ray Computed Tomography (CT) images in order to build binary masks that can be applied to functional images to infer information on the metabolic activity of the spinal marrow. This kind of information may be of particular interest for the study of the spinal marrow physiology in both health an...

BACKGROUND The spinal curvature in patients with Adolescent Idiopathic Scoliosis (AIS) causes an asymmetry of upper body postural alignment, which might affect postural balance. However, the currently available studies on balance in AIS patients are not consistent. Furthermore, it is not known whether potential deficits are similar between patients with single and double curves. Finally, the ef...

In this paper simple quartic trigonometric polynomial blending functions, with a tensionparameter, are presented. These type of functions are useful for constructing trigonometricB´ezier curves and surfaces, they can be applied to construct continuous shape preservinginterpolation spline curves with shape parameters. To better visualize objects and graphics atension parameter is included. In th...

various scaling methods such as relative viscosity, peclet and reynolds scaling were used to find the best scaling law. scaling and modeling of the flow curves of various model emulsions consist of tragacanth gum (tg) (0.5, 1 % wt), oleic acid (5, 10% v/v) and wpi (2, 4 % wt) were investigated and the best models were selected. as these emulsions are non-newtonian, they do not obey the usual, si...

‎In the present study‎, ‎we consider a regular curve in Galilean‎ ‎$4$-space $mathbb{G}_{4}$ whose position vector is written as a‎ ‎linear combination of its Frenet vectors‎. ‎We characterize such‎ ‎curves in terms of their curvature functions‎. ‎Further‎, ‎we obtain‎ ‎some results of rectifying‎, ‎constant ratio‎, ‎$T$-constant and‎ ‎$N$-constant curves in $mathbb{G}_{4}$‎.