Filtered back projection (FBP) method and maximum likelihood expection maximization (OSEM) method are currently used for reconstruction of SPECT images in clinical studies. The aim of this work is to compare the image quality using different reconstruction techniques of a SPECT phantom as applied to bone scintigraphy. The resolution and contrast of the hot spheres were observed using a phantom ...

Since the 1990s, hybrid imaging by means of software and hardware image fusion alike allows the intrinsic combination of functional and anatomical image information. This review summarises in three parts the state-of-the-art of dual-technique imaging, with a focus on clinical applications. We will attempt to highlight selected areas of potential improvement of combined imaging technologies and ...

Hybrid scanners, which enable the performance of single photon emission computed tomography (SPECT) and X-ray computed tomography (CT) in one imaging session, have considerable diagnostic potential. However, evaluating the anatomical accuracy of image fusion inherent to these systems remains a challenge. This paper proposes a method for evaluating this variable with minimum user interaction. It...

UNLABELLED Myocardial perfusion imaging with SPECT (SPECT-MPI) and 64-slice CT angiography (CTA) are both established techniques for the noninvasive evaluation of coronary artery disease (CAD). Three-dimensional (3D) SPECT/CT image fusion may offer an incremental diagnostic value by integrating both sets of information. We report our first clinical experiences with fused 3D SPECT/CT in CAD pati...

We are investigating interventional MRI (iMRI) guided thermal ablation treatment of the prostate cancer. Functional images such as SPECT can detect and localize tumor in the prostate not reliably seen in MRI. We intend to combine the advantages of SPECT with iMRI-guided treatments. Our concept is to first register the low-resolution SPECT with a high resolution MRI volume. Then by registering t...

A prototype of a combined CT–SPECT tomograph for breast cancer study has been developed and evaluated. It allows to perform scintimammography and X-ray CT in the same geometrical conditions. The CT system is based on a quasi-monochromatic beam tuned at 28 keV and an array of ultra fast ceramic scintillators coupled to photodiodes whilst the SPECT system is based on two scintillator matrices cou...

Thanks to its ability to yield functionally rather than anatomicallybased information, the SPECT imagery technique has become a great help in the diagnostic of cerebrovascular diseases. Nevertheless, SPECT images are very noisy and consequently their interpretation is difficult. In order to facilitate this visualization, we propose an unsupervised 3D Markovian model allowing to segment a brain ...

spect detects γ-rays from administered radiopharmaceutical within the patient body. γ-rays pass through different tissues before reaching detectors and are attenuated. attenuation can cause artifacts; therefore different methods are used to minimize attenuation effects. in our study efficacy of chang method was evaluated for attenuation purpose, using a custom made heart phantom. due to differe...

Multi-modality imaging provides coregistered PET-CT and SPECT-CT images; however such multi-modality workflows usually consist of sequential scans from the individual imaging components for each modality. This typical workflow may result in long scan times limiting throughput of the imaging system. Conversely, acquiring multi-modality data simultaneously may improve correlation and registration...

99mTc-HM-PAO single photon emission computed tomography (SPECT) was used to image 30 patients referred for the assessment of dementia. SPECT images revealed various patterns of regional cerebral perfusion (rCBF) in the subgroups of patients with the clinical diagnoses of Alzheimer's disease (AD, n = 14), Pick's disease (n = 1), and multi-infarct dementia (n = 7). In three patients, SPECT clarif...