BACKGROUND The routine use of biomonitoring (i.e., measurement of environmental chemicals, their metabolites, or specific reaction products in human biological specimens) to assess internal exposure (i.e., body burden) has gained importance in exposure assessment. OBJECTIVES Selection and validation of biomarkers of exposure are critical factors in interpreting biomonitoring data. Moreover, t...

The aim of this book is to improve communication between surgeons and histopathologists. It reflects the 'team' approach to clinical management, and takes the form of a series of chapters on 35 surgical topics. Each chapter is written by a pair of surgeons and pathologists, most of whom work in the same hospital. Probably the most illuminating section is the editorial introduction, in which the...

These guidelines are intended to facilitate the dissection and reporting of those tumours of the larynx, hypopharynx, and piriform fossa that may be treated by laryngectomy. The guidelines incorporate the core data for histopathology reports on head and neck carcinomas previously published by the Royal College of Pathologists which indicate the information required, in addition to clinical data...

Personalized medicine promises diagnosis and treatment of disease at the individual level and relies heavily on clinical specimen integrity and diagnostic assay quality. Preanalytics, the collection and handling steps of a clinical specimen before immunohistochemistry or other clinical assay, are critically important to enable the correct diagnosis of disease. However, the effects of preanalyti...

BACKGROUND In the changing world of clinicopathologic practice where surgeons and pathologists are faced with increasing therapeutic demands, precise demands of each group from the other have often been reduced to blames and counter-blames. This study is thus aimed at auditing the current practice of specimen handling as a means of highlighting areas where mutual best practice is required. MA...

Acoustic droplet ejection (ADE) is a powerful technology that supports crystallographic applications such as growing, improving and manipulating protein crystals. A fragment-screening strategy is described that uses ADE to co-crystallize proteins with fragment libraries directly on MiTeGen MicroMeshes. Co-crystallization trials can be prepared rapidly and economically. The high speed of specime...

the effects of dietary nucleotide (nt) were evaluated on some serum biochemical parameters and acute stress responses of the catfish (pangasianodon hypophthalmus). five experimental diets including 0, 0.25, 0.5, 0.75, and 1% nt were supplied to catfish fry for 10 weeks. at the end of the experiment, fish fed the control and 1% nt diets were subjected to handling and crowding stress. the results...

chemotherapy medication errors may lead to potentially harmful consequences while most of them could be preventable. this study aims to determine the incidence and type of drug handling and administration errors among the nurses and to identify possible contributing factors. setting of the study was a teaching hospital affiliated to shahid beheshti university of medical sciences, tehran, iran. ...

Abstract Handling robots are widely used today, and non-fixed handling is more effective than fixed in some specific scenarios. The of can increase the load reduce precise positioning process grabbing object, but velocity relatively slow for stability object. In addition, it needs to consider friction reaction force constraints on This paper proposes a high-velocity method robot. First, deduces...