We report a novel magnetic immunoassay technique using a SERS-based microdroplet sensor. The proposed method provides a rapid and sensitive assay applicable to PSA cancer markers in serum. The sensor used in this study consisted of four distinct compartments that function that act to generate microdroplets, separate immunocomplexes and supernatant solution, isolate magnetic immunocomplex drople...

wnloade pose: The relationship between prostate-specific antigen (PSA) level and prostate cancer risk resubject to fundamental disagreements. We hypothesized that the risk of prostate cancer on biopsy iven PSA level is affected by identifiable characteristics of the cohort under study. erimental Design: We used data from five European and three U.S. cohorts of men undergoing y for prostate canc...

A biomarker is a chemical in the body. Certain biomarkers can show when something unusual is going with certain bodily processes. One of the most commonly known and tested biomarkers is prostate specific antigen (PSA). Higher levels of PSA in the blood indicate a problem with the prostate. The difficulty is that the PSA test doesn’t tell us what kind of problem is affecting the prostate – wheth...

Failure of multiple components due to a common cause represents one of the most important issues in evaluation of system reliability or unavailability. The frequency of such events has relatively low expectancy, when compared to random failures, which affect individual components. However, in many cases the consequence is a direct loss of safety system or mitigative safety function. For this re...

CO2 reforming of methane (CRM) over unpromoted and potassium promoted Ni/Al2O3 catalysts was studied. The catalysts were prepared by impregnation method and characterized by X-ray diffraction (XRD), N2 adsorption (BET), temperature programmed reduction (TPR), temperature programmed oxidation (TPO) and scanning electron microscope (SEM) techniques. The obtained results showed that addition of K2...

In the present study, a type of graphitic mesoporous carbon (denoted as GMC) is synthesized and its structural properties were characterized by nitrogen physisorption isotherms, transmission electron microscopy and Raman spectroscopy. According to BET and BJH methods, the specific surface area (SBET) and the average pore diameter of GMC are estimated to be 720 m2/g and 3.4 nm, respectively....

This work describes the optical and structure properties of nickel sulfide and cobalt sulfide nanoparticles in ZSM-5 zeolite. The samples were obtained by sulfidation of the Ni2+ and Co2+ ion-exchange ZSM-5 zeolites in a Na2S solution at room temperature. The optical properties of the samples were studied by UV-visible spectroscopy. Their crystalline structure and morphology were studied by X-r...

OBJECTIVE To determine the efficacy of tinidazole for treatment of cats with experimentally induced Tritrichomonas foetus infection. ANIMALS 8 specific-pathogen-free kittens. PROCEDURES Tinidazole was tested for activity against a feline isolate of T foetus in vitro. Kittens were infected orogastrically with the same isolate and treated or not with tinidazole (30 mg/kg, PO, q 24 h for 14 da...

clinical effect. The authors recommend that the optimal time to obtain an accurate PSA level is fasting for 7–9 h, which avoids the increased PSA levels observed with fasting extremes as well as possible diurnal rhythm variations that may exist in shorter fasting times. This is an interesting study with meaningful results. The authors have addressed obvious limitations such as potential recall ...

Prostate cancer is a common male malignant disease worldwide. Its incidence rate varies widely between countries and ethnic populations. The incidence rates in Asian countries are much lower compared to Western countries. Environmental exposure, diet and lifestyle, as well as quality of the health care system and penetrance of prostate specific antigen (PSA) screening affect the reported incide...