It was recently found that the proteolytic enzymes trypsin (19 and chymotrypsin (2) possess specific esterase activity. In addition to catalyzing the hydrolysis of specific peptides (3-7), these enzymes also catalyze the hydrolysis of those esters which possess the structural environment of the specific peptides. In order to substantiate further the suggestion of Schwert et al. (1) that the spe...

A gait-recognition technique that recovers static body and stride parameters of subjects as they walk is presented. This approach is an example of an activity-specific biometric: a method of extracting identifying properties of an individual or of an individual’s behavior that is applicable only when a person is performing that specific action. To evaluate our parameters, we derive an expected ...

We demonstrated the in vivo feasibility of using focused ultrasound (FUS) to transiently modulate (through either stimulation or suppression) the function of regional brain tissue in rabbits. FUS was delivered in a train of pulses at low acoustic energy, far below the cavitation threshold, to the animal's somatomotor and visual areas, as guided by anatomical and functional information from magn...

Specific cutting of undamaged DNA by UvrABC nuclease is observed. It occurs seven nucleotides (nt) from the 3' terminus of oligonucleotides annealed to single-stranded M13 DNA circles. Although the location of the UvrABC cut on undamaged DNA is similar to that of the cut on the 5' side of a damaged DNA site during the dual incision reaction, the cut of undamaged DNA is not an intermediate in th...

The notion that atherosclerosis has an inflammatory component was already proposed in the 19th century by Virchow, on the basis of light microscopic analysis of human plaques. The hypothesis was later supported by electron microscopic studies and was confirmed when immunohistochemical analysis revealed that the CD141 macrophage indeed was the major cell type in the plaque.1,2 More surprising wa...

Digoxin-specific antibodies are capable of removing essentially all intracellular digoxin from rat renal cortical slices or from human erythrocytes. In removing digoxin from erythrocytes, these antibodies are capable of reversing an effect of the drug on cellular potassium transport. This study provides direct evidence that antibodies are capable of removing, and thereby reversing the biologica...

The discovery of relatively simple peptide derivatives as substrates for proteolytic enzymes has introduced a new approach to the problem of the specificity of this group of hydrolytic enzymes. Although crystalline trypsin is known to catalyze the hydrolysis of internal peptide bonds of proteins, its action toward internal peptide bondsof synthetic substrates has been demonstrated for only one ...

Introduction: This study covered the assessment of the natural radioactivity levels and heavy metalsconcentration in dust samples collected from selected schools in the holy Governorate of Karbala. The purpose of thisstudy was to assess the radiological health and safety impact of dust pollution on the children going to school. Material and Methods:</...