BACKGROUND Hand, foot, and mouth disease (HFMD) has caused major public health concerns worldwide, and has become one of the leading causes of children death. China is the most serious epidemic area with a total of 3,419,149 reported cases just from 2008 to 2010, and its different geographic areas might have different spatial epidemiology characteristics at different spatial-temporal scale leve...

This study examined the spatial distribution of childhood community-acquired pneumonia detected through prospective surveillance in Goiânia, Brazil. Three spatial analysis techniques were applied to detect intra-urban geographic aggregation of pneumonia cases: Kernel method, nearest neighbor hierarchical technique, and spatial scan statistic. A total of 724 pneumonia cases confirmed by chest ra...

BACKGROUND A variety of statistical methods have been suggested to assess the degree and/or the location of spatial clustering of disease cases. However, there is relatively little in the literature devoted to comparison and critique of different methods. Most of the available comparative studies rely on simulated data rather than real data sets. METHODS We have chosen three methods currently...

BACKGROUND Respiratory infections continue to be a public health threat, particularly to young children in developing countries. Understanding the geographic patterns of diseases and the role of potential risk factors can help improve future mitigation efforts. Toward this goal, this paper applies a spatial scan statistic combined with a zero-inflated negative-binomial regression to re-examine ...

Cluster detection is an important part of spatial epidemiology because it may help suggest potential factors associated with disease and thus, guide further investigation of the nature of diseases. Many different methods have been proposed to test for disease clusters. The most popular methods for detecting spatial focused clusters are circular spatial scan statistic (CSS), flexible spatial sca...

Information on the spatial distribution of plant disease can be utilized to implement efficient and spatially targeted disease management interventions. We present a pathogen-generic method to estimate the spatial distribution of a plant pathogen using a stochastic optimization process which is epidemiologically motivated. Based on an initial sample, the method simulates the individual spread p...

This dissertation consists of five papers and an introduction. In Barriers in travel models, the focus is on modelling mobility in border regions, both borders within nations and between nations. We use travel surveys and networks from Sweden and Norway to model the barrier effect caused by the borders in the region between two counties on each side of the national border. In Identifying local ...

Based on a local spatial/frequency representation,we employ a spectral histogram as a feature statistic for texture classification. The spectral histogram consists of marginal distributions of responses of a bank of filters and encodes implicitly the local structure of images through the filtering stage and the global appearance through the histogram stage. The distance between two spectral his...

Background: Leishmaniasis is a zoonosis disease. About 350 million people are at risk of developing a disease, with 1.5 to 2 million new cases every year in the world. The aim of this study was to determine the space-time clusters of cutaneous leishmaniasis in north of Khuzestan Province, Iran. Methods: In this cross-sectional study, the annual cutaneous leishmaniasis incidence per 100,000 ind...

Magnetoencephalography (MEG) is a method to measure a magnetic field generated by electrical neural activity in a brain, and it plays increasingly important role in clinical diagnoses and neurophysiological studies. However, in MEG analysis, the estimation of the brain activity, of the electric current density distribution in a brain which is represented by current dipoles, is problematic. A sp...