Background: IL17 inhibitors (IL17i) are an alternative for patients with axial spondyloarthritis (axSpA) who did not respond to TNF (TNFi). Secukinumab (SEC) is the first human monoclonal antibody that binds protein interleukin-17A. Objectives: The objectives of this study were describe characteristics axSpA treated IL17i and TNFi assess persistence in a real world cohort. Methods: A retrospect...

A prototype version of the ImmersiveTouch® virtual reality simulator was applied to capsulorhexis, the creation of circular tear or "rhexis" in the lens capsule of the eye during cataract surgery. Virtual and live surgery scores by residents were compared. The same three metrics are used in each mode: circularity of the rhexis, duration of surgery (sec), and number of forceps grabs of the capsu...

This study investigated the appropriate tourniquet pressure (TP) and duration of tourniquet application for venipuncture by calculating the venous cross-section (VCS) area on ultrasonography. Twenty healthy volunteers without cardiovascular risk factors were enrolled in this study. A target vein (either a cephalic or median cubital vein) was selected on ultrasonography. The pneumatic tourniquet...

Neutron bursts were produced by modulation of the arc source of a small cyclotron. Neutrons subsequently slowed down in paraffin were detected by a BF3ionization chamber and linear amplifier. Modulation of an additional amplifier allowed the counting of all detected. neutrons as well as those arriving in a specified time interval. Time of flight experiments were carried out at 3.0 meters with "...

Current software implementations of current cryptographic algorithms are orders of magnitude slower than required to secure a gigabit network. This paper examines three different approaches to improving the performance of cryptographic software: new algorithm design, parallelization, and algorithm independent hardware support. We believe that in combination these approaches could go a long way ...

To confirm that an increase in blood pressure induced by ketamine is mediated through the central nervous system, we examined effect of ketamine, applied directly to amygdala, on pressure. Six male Sprague-Dawley rats were used study. Under head-restrained and unanesthetized condition, 0.2 μl (5 mg/ml) was injected around amygdala at a flow rate μl/min glass pipette, recorded while monitoring s...

Selenoproteins are a unique group of proteins that contain selenium in the form of selenocysteine (Sec) co-translationally inserted in response to a UGA codon with the help of cis- and trans-acting factors. Mammalian selenoproteins contain single Sec residues, with the exception of selenoprotein P (SelP) that has 7-15 Sec residues depending on species. Assessing an individual's selenium status ...

BACKGROUND Right ventricular (RV) systolic performance is more difficult for evaluation compared to the left ventricle (LV). Despite differences in structure, RV myocardial fibers are in continuity with those of LV. The aim is assessment of the effects of LV wall motion abnormalities (WMA) on RV systolic function at rest and after stress. METHODS Fifty nine subjects, 15 with LV-WMA underwent ...