Sorbitol accumulation is postulated to play a role in skeletal muscle dysfunction associated with diabetes. The purpose of this study was to determine the effects of insulin and of endurance exercise on skeletal muscle sorbitol levels in streptozotocin-induced diabetic rats. Rats were assigned to one experimental group (control sedentary, control exercise, diabetic sedentary, diabetic exercise,...

INTRODUCTION Based on a single rat study by Lillemoe et al, the consensus has been formed to implicate sorbitol rather than sodium polystyrene sulfonate (SPS) as the culprit for colon necrosis in humans treated with SPS and sorbitol. We tested the hypothesis that colon necrosis by sorbitol in the experiment was due to the high osmolality and volume of sorbitol rather than its chemical nature. ...

In this research ,the efficacy of the sorbitol dehydrogenase enzyme was compared with immunoassay technology and laboratory method for diabetic patients in Mosul city .Types patient were divided to four groups whose ages range from (8-62) years both sexes (64 males 56 females).The first group who depend on their treatment insulin injection only known as typ1 diabetes classified, second classifi...

Background: Poisoning, a common worldwide problem, seeks its own treatments to improve, especially by the forthcoming evidence based medicine (EBM). Charcoal/sorbitol slurry (CSS) administration is one of these methods with great debates around it which needs to be investigated more. Methods: In this clinical trial, 105 cases of benzodiazepine toxicity with at least 3 symptoms and no contrain...