The x-ray crystal structures of trans-cinnamoyl-subtilisin, an acyl-enzyme covalent intermediate of the serine protease subtilisin Carlsberg, have been determined to 2.2-A resolution in anhydrous acetonitrile and in water. The cinnamoyl-subtilisin structures are virtually identical in the two solvents. In addition, their enzyme portions are nearly indistinguishable from previously determined st...

Two new mononuclear iron(II) compounds (1) and (2) of the general formula [Fe(L)₂](BF₄)₂·nCH₃CN (L = 4-(2-bromoethyn-1-yl)-2,6-bis(pyrazol-1-yl)pyridine, n = 1 for (1) and n = 2 for compound (2)), were synthesized. The room temperature crystallization afforded concomitant formation of two different solvent analogues: compound (1) exhibiting triclinic P-1 and compound (2) monoclinic C2/c symmetr...

The aim of this study was to extract oil from the seeds of Chia (Salvia hispanica L.) using different solvents (ethyl acetate, isopropanol and n-hexane) and varying the seed to solvent ratio. The fatty acids profiles of the oils were determined and technological analysis of the defatted meal was carried out. In relation to the oil extraction, higher yields were obtained with n-hexane and ethyl ...

"Film-through large perovskite grains formation via a combination of sequential thermal and solvent treatment" (2016). Organic–inorganic halide perovskites have recently attracted strong research interest for fabrication of high-performance, low-cost photovoltaic devices. Recently, we reported a highly reproducible procedure to fabricate high-performance organic–inor-ganic halide perovskite sol...

Cadmium is an extremely toxic metal, which even in low levels is harmful to the human body, animals and also plants. Human manufactures such as cadmium-nickel batteries and pesticides, plastic, make the earth polluted with cadmium; therefore removal of the cadmium Water is vital for human and animal. Scientists use different methods for cadmium removal including adsorption, precipitation, i...

The therapeutic benefit of microencapsulated drugs and vaccines brought forth the need to prepare such particles in larger quantities and in sufficient quality suitable for clinical trials and commercialisation. Very commonly, microencapsulation processes are based on the principle of so-called "solvent extraction/evaporation". While initial lab-scale experiments are frequently performed in sim...

We examined the ionization potential (IP) corresponding to the free energy of a hole on duplex DNA by semiempirical molecular orbital theory with a continuum solvent model. As for the contiguous guanines (a guanine run), we found that the IP in the gas phase significantly decreases with the increasing number of nucleotide pairs of the guanine run, whereas the IP in water (OP, oxidation potentia...

Pretreatment facilitates more complete deconstruction of plant biomass to enable more economic production of lignocellulosic biofuels and byproducts. Various co-solvent pretreatments have demonstrated advantages relative to aqueous-only methods by enhancing lignin removal to allow unfettered access to cellulose. However, there is a limited mechanistic understanding of the interactions between t...

Microencapsulated dosage forms represent effective new therapeutic platforms. This special issue will cover the different interests of microencapsulation as a means to control or modify the release of drug substances from drug delivery systems. To overcome the drug stability problem, since clinical efficacies have been reported to be improved by the encapsulation of pharmaceuticals, the bioavai...

Defatted bovine liver (DBL) is a potential source of protein and minerals. Supercritical carbon dioxide (SC-CO2) and a traditional organic solvent method were used to remove lipid from bovine liver, and the quality characteristics of a control bovine liver (CBL), bovine liver defatted by SC-CO2 (DBLSC-CO2) at different pressures, and bovine liver defatted by organic solvent (DBL-OS) were compar...