Abstract In the production of fermented cabbage, cell juice cabbage is released, which highly saturated in biologically active compounds, but considered as a by-product. The aim this study was to evaluate quality parameters dehydrated using maltodextrin coating agent at various concentrations. experiment, used — spray dried on horizontal spray-dryer and maltodextrin, different concentrations (0...

Proteolytic degradation of recombinant proteins represents a major problem related to production of gene products in heterologous hosts. Recombinant DNA technology offers several alternative strategies for stabilization of expressed gene products. These strategies can often give dramatic stabilization effects and can be combined with strategies involving optimization of fermentation conditions ...

Glycodiversification broadens the scope of natural product-derived drug discovery. The acceptor substrate promiscuity of glucosyltransferase-D (GTF-D), a carbohydrate-processing enzyme from Streptococcus mutans, was expanded by protein engineering. Mutants in a site-saturation mutagenesis library were screened on the fluorescent substrate 4-methylumbelliferone to identify derivatives with impro...

The ability to correlate fullerene solubility with experimentally or computationally accessible parameters can significantly facilitate nanotechnology nowadays for a wide range of applications, while providing crucial insight into optimum design of future fullerene species. To date, there has been no single relationship that satisfactorily describes the existing data clearly manifesting the eff...

The aim of this work was to study the main effects of acerola powder on fluidized bed agglomeration. A 2 fractional factoring design was used to evaluate the main operating conditions (fluidizing air temperature, fluidizing air velocity, atomizing air flow and height of nozzle in the bed). The mechanical and physicochemical product changes were determined by analysis of particle diameter, moist...

BACKGROUND The intention of this research was to prepare and compare various solubility-enhancing nanoparticulated systems in order to select a nanoparticulated formulation with the most improved oral bioavailability of poorly water-soluble fenofibrate. METHODS The most appropriate excipients for different nanoparticulated preparations were selected by determining the drug solubility in 1% (w...

Solid dispersions have been employed to enhance the dissolution rates of poorly water-soluble drugs. Many approaches have been investigated for the preparation of solid dispersions. This paper reports the various solubility enhancement strategies in solid dispersion. The approaches described are fusion (melting), solvent evaporation, lyophilization (freeze drying), melt agglomeration process, e...

Reactions in scCO2 are frequently limited by the low polarity of the solvent. This may result in low solute/ product solubility or low catalyst activity. The use of more polar sc fluids such as difluoromethane (HFC 32) can circumvent many of these issues and facilitate reactions that are not possible in CO2. We demonstrate the use of HFC 32 for three types of reaction; an esterification reactio...

Abstract—The composite flour blend consisting of corn, pearl millet, black gram and wheat bran in the ratio of 80:5:10:5 was taken to prepare the extruded product and their effect on physical properties of extrudate was studied. The extrusion process was conducted in laboratory by using twin screw extruder. The physical characteristics evaluated include lateral expansion, bulk density, water ab...