AIM To examine the efficacy and safety of prostaglandin E(1) incorporated into lipid microspheres (lipo-PGE(1)), Palux Injection, in patients with diabetic foot ulcers classified as ischemic, neuropathic, or neuroischemic at 108 medical institutions throughout Japan. METHODS A prospective observational study. RESULTS The safety and efficacy of the drug were analyzed in 388 and 280 patients,...

The literature, and particularly the statistical evaluation of peptic ulcer, is vast and ordinarily there should be little excuse for adding to it, unless one has some definite reason. It is well recognized that all over the world this disease pattern in the last few decades has undergone certain changes with regard to the duodenal-gastric ulcer ratio, sex incidence, and the occurrence of compl...

Background: Basic fibroblast growth factor (bFGF) is a glycoprotein with stimulating ability of angiogenesis. In addition, bFGF plays an important role in wound healing process in some tissues for example gastrointestinal tract, but its ability for discrimination of various stages of wound severity in these diseases was not reported. Therefore, we aimed to determine the bFGF levels in gastric u...

Background: Peptic ulcer has become an immense problem in our health care system. One of the major cause being overuse NSAIDs Pakistan.
 Objective: To evaluate gastro protection by Vitamin E, C and combination E on morphology aspirin induced gastric mucosal injury albino rats.
 Methodology: 45 adult rats were taken organized into 5 groups. Control was formed Group I. II given aspirin....

I was interested in the distribution of “non-trophic cutaneous ulcers” shown on the knuckles and dorsal foot in the case report of a 44-year-old female with multibacillary Hansen’s disease or leprosy. The case had glove stocking sensory and motor neuropathy and histopathology characteristics of multibacillary Ridley Jopling borderline lepromatous or lepromatous leprosy. The patient was treated ...

intercropping may be helpful manner to increase interception and utilization. the aim of this study was to compare radiation use efficiency and radiation interception in intercropping with sole cropping. an experiment was conducted at the agricultural research station, ferdowsi university of mashhad in the growing season of the year 2008. the experimental treatments were: 1- sole crop of bean 2...

The effect of alcoholic extract of Nigella sativa was investigated in rats to evaluate the anti-ulcer activity by using two models, i.e. pyloric ligation and aspirininduced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decre...

A 70-year-old man belonging to low socioeconomic status, illiterate, and daily-wage laborer, presented with painful, foul-smelling ulcer on the glans penis. The patient was examined properly and investigated thoroughly. When the ulcer was cleaned, maggots started emerging from the ulcer. They were removed by applying turpentine oil on the ulcer. The ulcer did not heal despite regular wound dres...

The rate of elective surgery for peptic ulcer disease has been declining steadily over the past 3 decades. During this same period, the rate of emergency ulcer surgery rose by 44%. This means that the gastrointestinal surgeon is likely to be called on to manage the emergent complications of peptic ulcer disease without substantial experience in elective peptic ulcer disease surgery. The goal of...