SIGNIFICANT reductions in caries activity have been reported by several investigators following the topical application of fluoride.t'3 Positive results were obtained in studies on children when treated mouth quadrants were compared with untreated quadrants in the same individuals. Arnold, Dean, and Singleton4 observed no reduction in caries activity when whole mouth treatments were applied to ...

Background and Aim: Since fluoride therapy is usually the first step of treatment in pediatric dentistry and it may interfere with other treatments, such as composite fill-ing, this study aimed to evaluate the possible effects of topical pre-fluoride therapy on marginal microleakage of composite restorations in deciduous teeth. Materials and Methods: In this in-vitro study, 30 deciduous canine...

The purpose of this study was to compare the effectiveness of toothbrushing followed by fluoride rinsing, fluoride gel brushing, or fluoride gel dentifrice brushing alone in controlling the demineralization that often follows orthodontic treatment. Seventy-eight consecutive adolescent patients undergoing orthodontic care were divided into 3 groups: group 1 (control) used a low-potency, high-fre...

BACKGROUND Glass ionomer (GI) restorations exposed to fluoride have the ability to slowly release fluoride. Therefore, the aim of this study was to investigate fluoride release from three GIs before and after exposure to sodium fluoride (NaF) and acidulated phosphate fluoride (APF). MATERIALS AND METHODS Fifteen disc-shaped samples (6 mm in diameter and 2 mm in thickness) from three GIs (Fuji...

Toothpastes should have a minimum concentration of 1000 ppm of fluoride (F) to control caries and also the active F agent must be chemically free (soluble) in the formulation. Thus, the aim of this study was to evaluate the concentration of soluble F in dentifrices used by 206 Brazilian children. The concentrations of total fluoride (TF), total soluble fluoride (TSF) and fluoride ion were deter...

We evaluated the concentration of fluoride release at the initial stage and after recharging the fluoride from a resin-based sealant containing surface reaction-type pre-reacted glass-ionomer (S-PRG) filler and conventional resin-based sealants. The concentration of other ions released from the sealants in the surrounding distilled water was also examined. At the initial stage, fluoride was rel...

DNA damage by fluoride to newborn rat kidney cells isolated by enzymic digestion is reported. The cells were exposed for 24 hr to sodium fluoride at NaF concentrations of 0, 0.2, 0.4, 0.8, and 1.0 mM. Damage to DNA was determined by single cell gel electrophoresis assay (Comet assay). Significant breakage of DNA strands occurred at 0.8 mM NaF and above. Compared with the control group, the come...

BACKGROUND This study evaluated the fluoride release and uptake of five common dental restoratives mainly glass ionomer formulations, including a conventional glass ionomer, a relatively new caries stabilization glass ionomer and resin-modified glass ionomer (Fuji II, Fuji VII and Fuji II LC); one compomer (F2000); and one fluoride releasing composite resin (tetric ceram). MATERIALS AND METHO...

Fluoride which is widespread in our environment and food due to its geological origin industrial pollution has been identified as a developmental neurotoxicant. Gut-brain axis provides new insight into brain-derived injury. We previously found the psychoactive effects of probiotic strain, Lactobacillus johnsonii BS15 against fluoride-induced memory dysfunction mice by modulating gut-brain axis....

OBJECTIVES The purpose of this study was to assess the effect of single and combined applications of fluoride on the amount of fluoride release, and the remineralization and physical properties of enamel. MATERIALS AND METHODS Each of four fluoride varnish and gel products (Fluor Protector, FP, Ivoclar Vivadent; Tooth Mousse Plus, TM, GC; 60 Second Gel, A, Germiphene; CavityShield, CS, 3M ESP...