Enhanced formation of nitric oxide (NO) by both the constitutive and the inducible isoforms of NO synthase (NOS) has been implicated in the pathophysiology of a variety of diseases, including circulatory shock. Non-isoform-selective inhibition of NO formation, however, may lead to side effects by inhibiting the constitutive isoform of NOS and, thus, the various physiological actions of NO. S-Me...

BACKGROUND Spinal manipulation therapy (SMT) is a popular though controversial practice. The debates surrounding efficacy and risk of SMT are only partially evident in popular discourse. OBJECTIVE This study aims to investigate the presence of critiques and debates surrounding efficacy and risk of SMT on the social media platform Twitter. The study examines whether there is presence of debate...

We present two methods that merge ideas from statistical machine translation (SMT) and translation memories (TM). We use a TM to retrieve matches for source segments, and replace the mismatched parts with instructions to an SMT system to fill in the gap. We show that for fuzzy matches of over 70%, one method outperforms both SMT and TM baselines.

The Satisfiability Modulo Theory (SMT) problem over floating-point arithmetic is a major hurdle in applying SMT techniques to real-world floatingpoint code. Solving floating-point constraints is challenging in part because floating-point semantics is difficult to specify or abstract. State-of-the-art SMT solvers still often run into difficulties when solving complex, non-linear floating-

BACKGROUND CONTEXT Despite the many published randomized clinical trials (RCTs), a substantial number of reviews and several national clinical guidelines, much controversy still remains regarding the evidence for or against efficacy of spinal manipulation for low back pain and neck pain. PURPOSE To reassess the efficacy of spinal manipulative therapy (SMT) and mobilization (MOB) for the manag...

Currently, only a few Satisfiability Modulo Theories (SMT) solvers are able to produce proof objects, although there is a strong incentive: Proof objects can be reconstructed in a different system to the check soundness of an SMT solver. We present proof reconstruction for the SMT solver Z3 in Isabelle/HOL and give experimental results of its application.

This paper serves as solver description for our SMT solver Boolector entering the SMT Competition 2014 in three different configurations. We only list important differences to the earlier version of Boolector that participated in the SMT Competition 2012 [2]. For further information we refer to [2] or source code.

A key driver of SMT over the past decade has been an interchange format, SMT-LIB, and a growing set of benchmarks sharing this common format. SMT-LIB captures very well an interface that is suitable for many tasks that reduce to solving first-order formulas modulo theories. Here we propose to extend these benefits into the domain of symbolic software model checking. We make a case that SMT-LIB ...

STUDY DESIGN Systematic review. OBJECTIVE We sought to answer the following clinical questions: (1) Is structured exercise more effective in the treatment of chronic low back pain (LBP) than spinal manipulative therapy (SMT)? (2) Is structured exercise more effective in the treatment of chronic LBP than acupuncture? (3) Is SMT more effective in the treatment of chronic LBP than acupuncture? (...

A core technique of modern tools for formally reasoning about computing systems is generating and dispatching queries to automated theorem provers, including Satisfiability Modulo Theories (SMT) provers. SMT provers aim at the tight integration of decision procedures for propositional satisfiability and decision procedures for fixed first-order theories – known as theory solvers. This thesis pr...