نتایج جستجو برای: small colon

تعداد نتایج: 853442  

2008
Toshio Fujisawa Michiko Sugiyama Ayako Tomimoto Koichiro Wada Hiroki Endo Hirokazu Takahashi Kyoko Yoneda Masato Yoneda Masahiko Inamori Satoru Saito Yasuo Terauchi Takashi Kadowaki Naoto Tsuchiya Hitoshi Nakagama Atsushi Nakajima

Although peroxisome proliferator-activated receptor γ (PPARγ) is strongly expressed in the intestinal epithelium, the role of PPARγ in intestinal tumorigenesis has not yet been elucidated. To address this issue, we investigated the effect of PPARγ inhibition and its mechanism on intestinal tumorigenesis using a selective antagonist, T0070907. We treated Apc /+ mice and carcinogen-induced colon ...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 1999
B R Grubb

Neonatal mice with cystic fibrosis (CF) exhibit a very high mortality due to intestinal obstruction localized primarily to the ileum and colon. It has been hypothesized that lack of Cl- secretion and possibly elevated Na+ absorption contribute to the gut problems in CF neonates. Therefore, intestines (ileum, proximal colon, and distal colon) from normal and CF day-old mouse pups were studied on...

Journal: :The Journal of endocrinology 1999
M Lefebvre B Paulweber L Fajas J Woods C McCrary J F Colombel J Najib J C Fruchart C Datz H Vidal P Desreumaux J Auwerx

Peroxisome proliferator-activated receptor gamma (PPARgamma), a fatty acid-activated nuclear receptor, is implicated in adipocyte differentiation and insulin sensitisation. In view of the association of dietary fat intake and bowel disease, the expression of PPARgamma in rodent and human intestine was studied. Expression of PPARgamma mRNA was examined by Northern blot hybridisation, RNase prote...

Journal: :Gut 1991
M Mantle E Atkins J Kelly E Thakore A Buret D G Gall

The effects of Yersinia enterocolitica on intestinal goblet cells were investigated in New Zealand white rabbits. Animals infected with Y enterocolitica were compared with weight matched and pair fed controls. Goblet cell hyperplasia developed in the distal small intestine of infected rabbits on day 1, in the mid small intestine on day 3, and in the upper small intestine on day 6. In all region...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2007
James M Amos-Landgraf Lawrence N Kwong Christina M Kendziorski Mark Reichelderfer Jose Torrealba Jamey Weichert Jill D Haag Kai-Shun Chen Jordy L Waller Michael N Gould William F Dove

Progress toward the understanding and management of human colon cancer can be significantly advanced if appropriate experimental platforms become available. We have investigated whether a rat model carrying a knockout allele in the gatekeeper gene Adenomatous polyposis coli (Apc) recapitulates familial colon cancer of the human more closely than existing murine models. We have established a mut...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2014
Zheng Wang Xing-Mao Zhang Hai-Tao Zhou Jian-Wei Liang Zhi-Xiang Zhou

BACKGROUND Despite the growing acceptance of laparoscopic colon surgery, an abdominal incision is needed to remove the specimen and perform an anastomosis. Recently, natural orifice specimen extraction (NOSE) and intracorporeal anastomosis have been proposed to minimize abdominal wall trauma and improve the quality of laparoscopic colon resections Objective: To evaluate the feasibility and safe...

Journal: :international journal of epidemiology research 0
azam sabahi birjand university of medical sciences, south khorasan, i.r. iran; student, kerman university of medical sciences, kerman, i.r. iran leila ahmadian medical informatics research center, institute for futures studies in health, kerman university of medical sciences, kerman, i.r. iran fatemeh salehi student, kerman university of medical sciences, kerman, i.r. iran sayed mahmoud mirzaee health center of ferdows, birjand university of medical sciences, south khorasan, i.r. iran.

background and aims: among all cancers, colon cancer is common and deadly, yet preventable. the estimated worldwide incidence of colon cancer is more than one million new cases per year. this study was done to identify the epidemiological features and risk factors of colon cancer in different regions of birjand. methods: this retrospective, descriptive analytical study of patients with colon ca...

Journal: :Gut 1991
L Biancone L S Wise K M Das

In patients with ulcerative colitis a colon tissue bound IgG and serum antibodies against an Mr 40,000 colonic protein(s) has been identified. Using an anti-Mr 40,000 protein monoclonal antibody, 7E12H12, by an immunocytochemical method, the protein was localised in human tissue exclusively to colonic epithelial cells. In this study the presence of the Mr 40,000 protein was assessed in experime...

Journal: :iranian journal of pathology 2016
mehrdad payandeh masoud sadeghi edris sadeghi

colorectal cancer (crc) metastasis to the thyroid gland is rare. here wereport a 45 yr-old man in western iran referred to hematology clinic, kermanshah city, iran in march 2014 with complaint of exertional dyspnea, multi-nodular goiter as well as complaint of exertional dyspnea, and multi-nodular goiter. his history included a low anterior resection of rectum in 9 months ago for a high-risk st...

2008
VL David A Radulescu O Adam M Banateanu P Tepeneu

Volvulus is a common surgical emergency and in most of the cases requires prompt diagnosis and treatment in order to evolve favorably. We present you a case of a 6year-old male with a massive volvulus involving a large portion of small bowel and sigma that did not evolve favorable. There are no prospective, randomized studies comparing treatment options and the most frequently raised questions ...

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