Unloading or disuse rapidly results in skeletal muscle atrophy, switching to fast-type fibers, and decreased resistance to fatigue. The recovery process is of major importance in rehabilitation for various clinical conditions. Here we studied mouse soleus muscle during 60 days of reloading after 4 wk of hindlimb suspension. Unloading produced significant atrophy of soleus muscle with decreased ...

The disposition and systemic vascular effects of bolus intravenous doses of diazoxide (3.75,7.5, and 15.0 mg/kg) were studied in anesthetized open-chest dogs. Blood flow (0) and right atrial pressure (Pra) were independently controlled by a right heart bypass. The late phase disposition halflife (beta t Vt) of diazoxide averaged 3.4 ± 0.5 hrs (x ± SEM) with an apparent volume of distribution at...

A comparison of the ability modifiers different classes to slow down aging processes occurring in petroleum bitumen during pavement operation is presented article. Oxidized and residual road bitumens were used as research objects. Determination resistance hardening under influence heat air was performed by RTFOT method. Samples oxidized with addition polymer resins hydroxyl functional groups he...

It has recently been suggested that general rules of change in ecological communities might be found through the development of functional relationships between species traits and performance. The physiological, behavioural and life-history traits of fishes are often organised along a fast-slow lifestyle continuum (FSLC). With respect to resistance (capacity for population to resist change) and...

Resting membrane potentials, electrical resistance, and coupling of chick retinal pigment epithelium cells in tissue culture have been measured with micropipette electrodes. Topical application of NaCl, KCl, MgCl2, and CaCl2 produce rapid, reversible changes in the membrane potentials of these cells. CaCl2 uniquely induces a slow hyperpolarizing wave that can lead to barrages of depolarizing ac...

Experiments are carried out with a chemical burster, the electrodissolution of iron in sulfuric acid solution. The system exhibits bursting oscillations in which fast periodic spiking is superimposed on chaotic, slow oscillations. Regularization of the slow dynamics, i.e., transition from chaotic to periodic bursting oscillations, is investigated through changes in the experimental parameters (...