OBJECTIVE It has been reported that untreated sleep-disordered breathing (SDB) deteriorates over time, however this remains contentious. The aim of the present study is to evaluate the clinical course of SDB in middle-aged and older SDB patients, and to identify how relevant factors contribute to the change in SDB severity. METHODS Baseline and follow-up polysomnographic data of 56 untreated ...

AIMS Sleep-disordered breathing (SDB) may be a risk factor for expansion of infarct size early after acute myocardial infarction (MI) by exposing the heart to repetitive oxygen desaturations and increased cardiac afterload. The objective of this study was to assess the impact of SDB on myocardial salvage and infarct size within 3 months after acute MI. METHODS AND RESULTS Patients with acute ...

Healthy sleep is essential in children's cognitive, behavioral, and emotional development. However, remarkably little is known about the influence of sleep disorders on different memory processes in childhood. Such data could give us a deeper insight into the effect of sleep on the developing brain and memory functions and how the relationship between sleep and memory changes from childhood to ...

The majority of patients with heart failure have sleep-disordered breathing (SDB)-with central (rather than obstructive) sleep apnoea becoming the predominant form in those with more severe disease. Cyclical apnoeas and hypopnoeas are associated with sleep disturbance, hypoxaemia, haemodynamic changes, and sympathetic activation. Such patients have a worse prognosis than those without SDB. Mask...

Stroke is prevalent in patients with sleep-disordered breathing (SDB). About 60% to 70% of all stroke patients are found to have SDB when defined by an apnea-hypopnea index (AHI) of more than 10 per hour.1 In addition, the presence of SDB (AHI ≥ 5) is also associated with a 2 to 4-fold increased risk of developing stroke.2,3 Several studies have shown an independent association between obstruct...

OBJECTIVES To examine associations between sleep-disordered breathing (SDB) and behavioral sleep problems (BSPs) through 5 years of age and special educational need (SEN) at 8 years. METHODS Parents in the Avon Longitudinal Study of Parents and Children reported on children's snoring, witnessed apnea, and mouth-breathing at 6, 18, 30, 42, and 57 months, from which SDB symptom trajectories, or...

1 Sin et al. American Journal of Respiratory Critical Care Medicine; 1999 2 Lafranchi et al. Circulation; 1999 3 Philippe et al. Heart; 2005 4 Javaheri et al. Circulation; 1998 5 Sin et al. American Journal of Respiratory Critical Care Medicine; 1999 Sleep-disordered breathing (SDB) is recognized as a serious health problem that impacts the cardiovascular system. Clinical studies have shown the...

The aim of our study was to investigate age-related changes in sleepiness symptoms associated with sleep disordered breathing (SDB). Wisconsin Sleep Cohort participants were assessed using polysomnography, the Epworth Sleepiness Scale (ESS) and the multiple sleep latency test (MSLT). SDB was defined as an apnoea/hypopnoea index ≥15 events·h(-1), and sleepiness as ESS ≥10 and MSLT ≤5 min. Odds r...

STUDY OBJECTIVES Experimental evidence indicates that alcohol use near bedtime may exacerbate sleep disordered breathing (SDB). However, scarce research has examined the relation between moderate habitual alcohol use and objectively assessed SDB, and it is unclear whether patients with SDB, or those at risk for SDB, should be counseled to avoid alcohol regardless of proximity to bedtime. In thi...

S leep-disordered breathing (SDB) represents a highly prevalent comorbidity in heart failure (HF) patients. Approximately 45% of stable patients with either heart failure with reduced ejection fraction (HFrEF) or preserved ejection fraction have moderate to severe obstructive sleep apnea (OSA) or central sleep apnea (CSA) (1,2), and this prevalence is even greater in patients with acutely decom...