Abstract Background IgLON5 disease is a novel autoimmune tauopathy with diverse sleep and neurologic manifestations. Sleep disorder common initial presentation may precede progression. Neurological symptoms frequently overlap extrapyramidal syndromes, motor neuron dementia. Diagnosis confirmed by anti-IgLON5 IgG in CSF and/or serum. Strong HLA-DRB1*1001 HLA-DQB1*0501 association supports mechan...

Sleep and sleep related disorders are involved in dementia pathogenesis. In particular, sleep quality, more than the sleep amount, plays a fundamental role in cognitive impairment. Mounting evidence implicates disturbed sleep or lack of sleep as one of the risk factors for Alzheimer’s disease (AD), but the extent of the risk is still uncertain. As sleep problems are of a growing concern in the ...

Sleep disordered breathing with or without nocturnal hypercapnic hypoventilation is a common complication of respiratory muscle weakness in childhood neuromuscular disorders. Nocturnal hypercapnic hypoventilation as a sign of respiratory muscle fatigue, portends a particularly poor prognosis. We aimed at identifying daytime predictors of sleep disordered breathing at its onset and sleep disorde...

INTRODUCTION Sleep apnea syndrome (SA) is a common breathing disorder that affects 5% of the North American adult population, with men being affected almost twice as much as women [1]. The condition has well defined associations with increased cardiovascular morbidity and mortality, arrhythmia, daytime hypersomnolence, motor vehicle accidents and neurocognitive dysfunction; but despite this it ...

Prader-Willi Syndrome (PWS) is a rare genetic disorder characterized by physical, psychological and physiological abnormalities. Obesity and related cardiovascular diseases are a common problem in adult patients with PWS. This report describes a case of adult PWS with heart failure associated with marked obesity and sleep-disordered breathing that was successfully treated with oxygen therapy, a...

BACKGROUND Sleep-disordered breathing is a common condition associated with adverse health outcomes including hypertension and cardiovascular disease. The overall objective of this study was to determine whether sleep-disordered breathing and its sequelae of intermittent hypoxemia and recurrent arousals are associated with mortality in a community sample of adults aged 40 years or older. METH...

background :work ability assessment and its affecting factors are important in the field of occupational health. one of the factors affecting work ability is sleep disorder, which is very common among workers. therefore, the present study aimed to assess work ability and its relationship with sleep disorder in workers of a manufacturing plant.   methods : this cross- sectional study was conduct...

BACKGROUND Allergy represents a risk factor at the base of sleep-disordered breathing in pediatric age. Among allergic diseases, the atopy is characterized by a tendency to be "hyperallergic." Sleep-disordered breathing is also known in orthodontics as correlated with the morphology of craniofacial complex. The aim of this study was to investigate the relation between atopy and sleep-disordered...

Humans are fortunate to have sleep. A happy, fulfilling life depends on getting a restful night of Obstructive sleep apnea is widespread disorder characterized by snoring loudly, difficulty breathing, and partial or complete lack Systemic side effects from chronic obstructive may affect the cardiovascular system other important body organs. Although exact cause unknown, number factors contribut...

Older adults have high prevalence rates of insomnia symptoms, yet it is unclear if these insomnia symptoms are associated with objective impairments in sleep. We hypothesized that insomnia complaints in older adults would be associated with objective differences in sleep compared with those without insomnia complaints. To test this hypothesis, we conducted a cross-sectional study in which older...