this experiment was performed to investigate whether feeding xylose-treated soybean meal (xsbm) or corn gluten meal (cgm) is economically better under field conditions. ninety-four multiparous early lactating holstein cows (55±5 days in milk and 2.82±0.41 body condition score) were used in a completely randomized design. cows were randomly assigned to one of two treatments: xsbm or cgm as the m...

Abstract We present and numerically analyse the Basin Hopping with Skipping (BH-S) algorithm for stochastic optimisation. This replaces perturbation step of basin hopping (BH) a so-called skipping mechanism from rare-event sampling. Empirical results on benchmark optimisation surfaces demonstrate that BH-S can improve performance relative to BH by encouraging non-local exploration, is, between ...

OBJECTIVES To examine the association between skipping breakfast, daily energy, macronutrients and food intakes, and BMI in pre-school children. DESIGN A cross-sectional study using information on children's food consumption and measured height and weight. Energy and macronutrient intakes of the children were derived from parent/day-care attendant's responses to 24 h recall interviews and eat...

A nonsense mutation in the fibrillin-1 (FBN1) gene of a Marfan syndrome (MFS) patient induces in-frame exon skipping of FBN1 exon 51. We present evidence, based on both in vivo and in vitro experiments, that the skipping of this exon is due to the disruption of an SC35-dependent splicing enhancer within exon 51. In addition, this nonsense mutation induces nonsense-mediated decay (NMD), which de...

BACKGROUND Antisense-mediated exon skipping is a putative treatment for Duchenne muscular dystrophy (DMD). Using antisense oligonucleotides (AONs), the disrupted DMD reading frame is restored, allowing generation of partially functional dystrophin and conversion of a severe Duchenne into a milder Becker muscular dystrophy phenotype. In vivo studies are mainly performed using 2'-O-methyl phospho...

BACKGROUND Breakfast eating habits are a dietary pattern marker and appear to be a useful predictor of a healthy lifestyle. Many studies have reported the unhealthy effects of skipping breakfast. However, there are few studies on the association between skipping breakfast and mortality. In the present study, we examined the association between skipping breakfast and mortality from cancer, circu...

The purpose of this study was to further explore the association between bullying victimization and breakfast skipping in children and adolescents. Compared to the previous study, we have used a larger and representative sample of middle and high school students, examined the effect of gender, different forms (physical, verbal, theft/vandalism and cyber) and severity of bullying on breakfast ea...

This study was performed to determine the optimum level of soybean meal diets for two banded sea bream for growth performance, nutrient utilization, body composition and serum biochemistry. Two banded seabream were fed five experimental diets which were formulated replace fish meal by soybean meal at 0, 20, 30, 40 and 50%. Up to 40% of dietary fish meal was successfully replaced with no growth...

We describe three case studies illustrating the use of ACL2s to prove the correctness of optimized reactive systems using skipping refinement. Reasoning about reactive systems using refinement involves defining an abstract, high-level specification system and a concrete, low-level implementation system. Next, one shows that the behaviors of the implementation system are allowed by the specifica...

Duchenne muscular dystophy (DMD) is a severe muscle wasting disease caused by mutations in the dystrophin gene. By utilizing antisense oligonucleotides, splicing of the dystrophin transcript can be altered so that exons harbouring a mutation are excluded from the mature mRNA. Although this approach has been shown to be effective to restore partially functional dystrophin protein, the level of d...