PURPOSE Cone beam computed tomography (CBCT) is fast becoming standard on modern linear accelerators. CBCT increases the dose to regions within and outside the treatment field, potentially increasing secondary cancer induction and toxicity. This study quantified megavoltage (MV) CBCT skin dose and compared it to skin dose delivered during standard tangential breast radiotherapy. METHOD Dosime...

Methods: Penetration studies according to OECD guidelines [1] were performed using skin samples taken from porcine ear. For enhancing the transport of the contrast agent into the skin a submicron emulsion containing 1mmol/ml Gadolinium (Gadobutrol, Gadovist, Schering, Germany) was used. The experiments were performed using the Franz-Diffusion-Cell setup, a standard device for in vitro penetrati...

Erythema occurs in 80-90% of women treated for breast cancer with radiation therapy. There is currently no standard treatment for radiation-induced skin reactions. This study investigates the clinical efficacy of Mepilex Lite dressings in reducing radiation-induced erythema in women with breast cancer. A total of 28 patients were recruited; of these, 24 participants presented with 34 erythemato...

The skin dose associated with radiotherapy may be of interest for clinical evaluation or investigating the risk of late effects. However, skin dose is not intuitive and is difficult to measure. Our objectives were to develop and evaluate a general estimation technique for skin dose based on treatment parameters. The literature on skin dose was supplemented with measurements and Monte Carlo simu...

Tunnel coupling is a key parameter in coupled semiconductor quantum dots, and crucial ingredient various device applications, such as exchange gates spin shuttling information processing. A widely used charge-sensing technique to extract the tunnel of double dot accounts for only ground orbital state each dot, but authors show that Si valley-orbit must be included analysis. With their more comp...

Introduction: Total skin electron irradiation technique is used in treatment of the mycosis fungoid. The implementation of this technique requires non-standard measurements and complex dosimetry methods. Operating procedures for total skin electron irradiation and its dosimetry vary in different radiation therapy centers in the world. In this article, validation of TSET techniq...

We investigated the neonatal entrance-surface dose (ESD) and doses of scattered radiation emitted by a digital mobile X-ray system. The system is equipped with a novel flat-panel detector and is used in the neonatal intensive care unit. In the present study, the following three experiments were performed on frequently used X-ray-imaging condition: (1) the digital characteristics of the FPD were...

Key applications of quantum computing, including error correction, rely critically on the capability to measure (read out) state selected bits, without disturbing other qubits or terminating computation. Such $m\phantom{\rule{0}{0ex}}i\phantom{\rule{0}{0ex}}d\phantom{\rule{0}{0ex}}c\phantom{\rule{0}{0ex}}i\phantom{\rule{0}{0ex}}r\phantom{\rule{0}{0ex}}c\phantom{\rule{0}{0ex}}u\phantom{\rule{0}{...

Three-dimensional (3D) organ-mimicking phantoms provide realistic imaging environments for testing various aspects of optical systems, including for evaluating new probe designs, characterizing the diagnostic potential of new technologies, and assessing novel image processing algorithms prior to validation in real tissue. We introduce and characterize the use of a new material, Dragon Skin (Smo...

This Letter introduces a feasibility study of a scanning system for applications in biomedical bone imaging operating in the microwave range 0.5-4 GHz. Mechanical uncertainties and data acquisition time are minimised by using a fully automated scanner that controls two antipodal Vivaldi antennas. Accurate antenna positioning and synchronisation with data acquisition enables a rigorous proof-of-...