Quantifiable prognostic indicators are of considerable practical value following thermal injury. Collagen is a major component of the skin, and is known to undergo denaturation at the elevated temperatures associated with burns. The purpose of this study was to determine whether a recently developed, non-invasive imaging technique could detect and quantify collagen denaturation in burned human ...

INTRODUCTION Four employees at a chemical plant sustained extensive chemical burns following the explosion of a pipeline containing 100% sulphuric acid. We describe the management of these patients from the initial ED triage through to discharge from hospital in life and limb threatening chemical burns. METHODS Four patients who sustained chemical burns to the torso and extremities are review...

Burns not only damage the skin barrier, but also cause a series of inflammatory reactions and oxidative stress states. Among them, elderly patients are prone to suffer severe burns due degenerative changes their caused by aging factors, such as atrophy thinning, etc. After burns, body will continuously release resulting in systemic response syndrome (SIRS) stress, which related poor treatment e...

The treatment of full thickness skin wounds commonly associated with large burns continues to represent a challenging clinical entity. The current treatment for large TBSA burns is split thickness autologous skin grafting; however, this treatment often results in poor textural durability, hypertrophic scarring, and fibrotic contractures. In this case report, we describe our experience and long-...

Health effects of acute exposure • The main routes of exposure to hydrogen chloride are via inhalation, or skin or eye contact and exposure to hydrochloric acid is predominantly by ingestion, or skin or eye contact • Inhalation may cause irritation to nose and upper respiratory tract, ulceration, coughing, chest tightness and shortness of breath. Higher concentrations cause tachypnoea, pulmonar...

INTRODUCTION Contractures, ectropion and scarring, the most common sequelae of skin grafts after eyelid burn injuries, can result in corneal exposure, corneal ulceration and even blindness. Split-thickness or full-thickness skin grafts are commonly used for the treatment of acute eyelid burns. Plasma exudation and infection are common early complications of eyelid burns, which decrease the succ...

Exposure to giant hogweed brings about the risk of serious skin damage, usually in the form of phytophotodermatitis. Initially, skin changes are signaled by a burning sensation, followed by a vesiculobullous rash and long-term hyperpigmentation. Usually, skin disorders improve after the application of topical and oral corticosteroids. In extremely rare instances, full skin thickness burns or ep...

Under normal conditions, the skin has a mean pH of 5.5, kept constant by the skin’s pH regulating barrier function. Variations tending towards higher or lower values are rapidly brought into line with the base value. This barrier function is efficacious at the age intervals between early infancy (6 months to 1 year) and advancing age (65-70 years). Prior to this interval and subsequent to it, t...