BACKGROUND Treatment of cerebral sinus thrombosis with thrombolytics has been reported in cases with a deteriorating clinical course despite anticoagulant therapy. The rationale of this treatment is to promote rapid recanalisation of the occluded sinus. OBJECTIVES To review the available evidence on the efficacy and safety of thrombolysis in confirmed cerebral sinus thrombosis. SEARCH STRAT...

Dural sinus thrombosis (DST) usually involves the sagittal, transverse and sigmoid sinuses and is more common in women due to pregnancy, puerperium and oral contraceptive use. Other etiologies include coagulopathies, infection and head injury. We have present two DST cases following head injury. The first case was a 35-year-old man hospitalized because of one-week history of headache and repeat...

Objective: To identify new factors influencing the onset of intracranial otogenic complications in adults. Study Design: Retrospective cohort Place and Duration Study: Department ENT, Nowshera Medical College, Qazi Complex from 1st October 2019 to 31st 2020. Methodology: One thousand nine hundred cases within age 40-78 years were enrolled. The data before viral pandemic corona virus was compare...

Demailly D, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220344 Description An 86-year-old woman with acute blunt head trauma (the patient’s head was hit by a car) 10 days ago, associated with a right occipital fracture and an acute subdural haematoma (treated in the department of neurosurgery by oral prednisone 80 mg once a day) (figure 1), presented with focal left arm motor seizures. At th...

Patients with inflammatory bowel disease (IBD) have an elevated risk of venous thromboembolism compared with the general population. The most common sites of venous thromboembolism in IBD patients are the deep veins of the legs, the pulmonary system, and portal and mesenteric veins. However, cerebral venous thrombosis is rarely associated with IBD. This report describes a case of cerebral venou...

BACKGROUND AND PURPOSE Little is known about the gender-specific manifestations of cerebral venous and sinus thrombosis, a disease that is much more common in women than men. METHODS We used data of the International Study on Cerebral Vein and Dural sinus Thrombosis (ISCVT), a multicenter prospective observational study, to analyze gender-specific differences in clinical presentation, etiolog...

OBJECTIVE The objective of this study was to define the relative contributions of three major pro- and anti-coagulation pathways (heparin-antithrombin, protein C, and tissue factor (TF)) in the thrombogenic responses that occur in large and small vessels of the brain. METHODS Cerebral venous sinus thrombosis was induced by topical application of FeCl3 on the superior sagittal sinus, while pho...

Cerebral venous sinus thrombosis (CVST) is a severe and rare pregnancy complication. The most common symptom headache. However, it less for headaches to be accompanied by seizures. Postpartum eclampsia (PPE) traditionally refers convulsions within seven days, but can occur up 4 weeks after birth. In this case report, we present our patient who developed cerebral thrombosis, which very complicat...