BACKGROUND False-positive radioiodine (RAI) uptake related to chronic sinusitis and mucocele has only rarely been reported in patients with differentiated thyroid cancer (DTC) even with the recent use of single photon emission tomography with computed tomography (SPECT/CT) acquisition. No other etiology of sinus RAI uptake has been mentioned to date. OBJECTIVES We report five cases of DTC pat...

High resolution yttrium-90 ((90)Y) imaging of post-radioembolization microsphere biodistribution may be achieved by conventional positron emission tomography with integrated computed tomography (PET/CT) scanners that have time-of-flight capability. However, reconstructed (90)Y PET/CT images have high background noise, making non-target activity detection technically challenging. This educationa...

[TOP] Dopamine transporter imaging with single photon emission computed tomography (DAT-SPECT) is investigational for all indications, including but not limited to:  Aiding in the diagnosis of patients with clinically uncertain parkinsonian syndromes; OR  Distinguishing between parkinsonian syndromes and essential tremor; OR  Distinguishing between dementia with Lewy bodies and Alzheimer dis...

We apply a uniform Cramer-Rao (CR) bound [l] to study the bias-variance trade-offs in parameter estimation. The uniform CR bound is used to specify achievable and unachievable regions in the bias-variance trade-off plane. The applications considered in this paper are: 1) twodimensional single photon emission computed tomography (SPECT) system, and 2) one dimensional edge localization.

As the world's population ages, the number of patients with Alzheimer's disease (AD) is predicted to increase rapidly. The presence of neurofibrillary tangles (NFTs), composed of hyperphosphorylated tau protein, is one of the neuropathological hallmarks of AD brain. Since the presence of NFTs is well correlated with neurodegeneration and cognitive decline in AD, imaging of tau using positron em...

Hybrid scanners, which enable the performance of single photon emission computed tomography (SPECT) and X-ray computed tomography (CT) in one imaging session, have considerable diagnostic potential. However, evaluating the anatomical accuracy of image fusion inherent to these systems remains a challenge. This paper proposes a method for evaluating this variable with minimum user interaction. It...

Regional CBF (rCBF) and regional cerebral blood volume (rCBV) were evaluated by N,N,N'-trimethyl-N'-(2)-hydroxy-3-methyl-5-[123I]iodobenzyl-1, 3-propanediamine-2 HCl- and 99mTC-labeled red blood cells, respectively, and single-photon emission computerized tomography (SPECT) in a patient with focal cerebral ischemia. Sequential transmission computerized tomography (TCT) and SPECT functional data...