Feeding, eating and deglutition difficulties are key concerns in patients with cardiofaciocutaneous syndrome (CFCS). This study intends to quantify the development of feeding skills from birth adulthood CFCS. Twenty-seven (eight males; mean age: 16.7 ± 8.3 years; median 15 years, age range: 1.5–38 years) molecularly confirmed clinical diagnosis CFCS were prospectively recruited Rare Disease Uni...

was brought to hospital on the morning of t'he 7th May 1926, with his tongue enormously swollen. The history was that this condition had started insidiously the previous night. So enormously swollen was the tongue that the boy could not completely close his mouth, and it was impossible to see the back of his throat. Respiration was carried on through the nose, and was 26 per minute, while the p...

Objective: To determine the influence of oral fluid sampling methods on drug concentrations. Methods: Oral fluid was obtained from 249 subjects by Varian OraLab and Statsure Saliva•Sampler. The OraLab consists of foam-tipped oral fluid collector. The sponge contains a salt that stimulates salivation. The Saliva•Sampler consists of a collector with a blue indication when 1 mL of oral fluid is co...

The present report is a study on the side effects experienced by the patients attending the Lithium Clinic of the Institute of Psychiatry, Government Rajaji Hospital, Madurai. Out of the 120 (M 78, F42) patients studied, 97 had side effects. The effects were examined in respect of their frequency, time of onset and course, their relation to one dose and serum levels of lithium and to the clinic...

Male and female albino rats given different oral doses (0.75, 2.5, 5.0 and 0.25, 0.75, 1.5 mg/kg/D) of endosulfan respectively for a period of 30 days elicited signs of toxicity such as hyperexcitability, tremor, dyspnea and salivation for a brief period. At the tested dose levels, endosulfan produced no significant change in the organ body weight ratio, biochemical, histological, haematologica...

Whenever a newborn infant presents with excessive salivation and failure to pass nasogastric tube, one of the 5 major types of esophageal atresia is suspected. We report a rare case where a newborn infant presented with features of esophageal atresia due to membranous diaphragm.

OBJECTIVE To determine the frequency of nonspecific clinical signs in dogs with separation anxiety, thunderstorm phobia, noise phobia, or any combination of these conditions and determine whether these conditions are associated in dogs. DESIGN Case series. ANIMALS 141 dogs. PROCEDURE Diagnoses were established using specific criteria. Owners of dogs completed a questionnaire on how freque...

Isoflurane was compared with halothane as the sole supplement to anaesthesia with nitrous oxide and oxygen for outpatient dental extractions in 80 children. Induction and maintenance of anaesthesia were satisfactory with both agents, although there was a higher incidence of coughing, salivation and laryngospasm in the group receiving isoflurane. However, in contrast to predictions from the phys...