The shrinkage estimate of a quantitative trait locus (QTL) effect is the posterior mean of the QTL effect when a normal prior distribution is assigned to the QTL. This note gives the derivation of the shrinkage estimate under the multivariate linear model. An important lemma regarding the posterior mean of a normal likelihood combined with a normal prior is introduced. The lemma is then used to...

Pyroplastic deformation is a distortion of the ceramic shape during the sintering process. It occurs because the flow of the vitreous phase at high temperature and the applied stress due to the weight of the product during sintering process. The aim of this paper deals with describing a numerical-experimental method to evaluate the pyroplastic deformation, to predict the anisotropic shrinkage a...

Background: Activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. Platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apoptosis disperse surfaces containing procoagulant activity around injured vessels and tissues. This study was conducted to determine microparticles formation and platelet shrinkage ...

To identify protein kinases (PK) and phosphatases (PP) involved in regulation of the Na+-K+-2Cl-cotransporter in Ehrlich cells, the effect of various PK and PP inhibitors was examined. The PP-1, PP-2A, and PP-3 inhibitor calyculin A (Cal-A) was a potent activator of Na+-K+-2Cl-cotransport (EC50 = 35 nM). Activation by Cal-A was rapid (<1 min) but transient. Inactivation is probably due to a 10%...

In this study, the early-age strain–stress development of mixtures containing slag cement was measured on uniaxially restrained specimens using a specially designed testing frame starting right after casting. It was found that thermal deformation dominates early-age stress development in low w/cm and low slag cement paste systems. While for concrete, autogenous shrinkage is the major contributi...

The objectives of this study were to compare the polymerization shrinkage of three orthodontic adhesives. In addition we wanted to determine the effectiveness of the high-intensity quartz tungsten halogen (HQTH) in curing orthodontic adhesives on polymerization shrinkage with that of the quartz tungsten halogen (QTH). A total of 120 glass ring molds were prepared using a low-speed saw. The inte...

While the conditional mean is known to provide the minimum mean square error (MSE) forecast – and hence is optimal under a squared-error loss function – it must often in practice be replaced by a noisy estimate when model parameters are estimated over a small sample. Here two results are obtained, both of which motivate the use of forecasts biased toward zero (shrinkage forecasts) in such setti...

Soft wavelet shrinkage, total variation (TV) diffusion, TV regularization, and a dynamical system called SIDEs are four useful techniques for discontinuity preserving denoising of signals and images. In this paper we investigate under which circumstances these methods are equivalent in the one-dimensional case. First, we prove that Haar wavelet shrinkage on a single scale is equivalent to a sin...

PURPOSE The purpose of this study was to compare the linear sintering behavior of presintered zirconia blocks of various densities. The mechanical properties of the resulting sintered zirconia blocks were then analyzed. MATERIALS AND METHODS Three experimental groups of dental zirconia blocks, with a different presintering density each, were designed in the present study. Kavo Everest® ZS bla...

In modern research, development of monomers that reduce shrinkage of composite materials remains an ongoing quest and perennial challenge. The purpose of this study, therefore, was to analyze the shrinkage behaviour of an innovative composite material for dental restorations based on a monomer with a new chemical formulation, known as silorane. To this end, shrinkage stress development during c...