Factors implicated in the pathophysiology of ulcerative colitis (UC) are an abnormal immune response, defect in intestinal epithelial barrier function, and gut microbiota. Currently, it is unclear whether specific bacterial strains are responsible for the induction of intestinal inflammation, but increased bacterial tissue invasion has been described in affected UC patients. Further, a quantita...

Urban environments present novel and challenging habitats to wildlife. In addition to well-known difference in abiotic factors between rural and urban environments, the biotic environment, including microbial fauna, may also differ significantly. In this study, we aimed to compare the change in microbial abundance on eggshells during incubation between urban and rural populations of a passerine...

shigella species (spp.) are gram-negative bacteria that are responsible for shigellosis. although it can be controlled via antibiotics, increasing number of antibiotic resistant isolates of shigella have been reported. therefore, other strategies such as production of specific vaccine against this organism could be a suitable therapeutic approach. attenuated live vaccines produced by gene delet...

Many human Gram-negative bacterial pathogens express a Type Three Secretion Apparatus (T3SA), including among the most notorious Shigella spp., Salmonella enterica, Yersinia enterocolitica and enteropathogenic Escherichia coli (EPEC). These bacteria express on their surface multiple copies of the T3SA that mediate the delivery into host cells of specific protein substrates critical to pathogene...

INTRODUCTION The etiological and clinical characteristics of patients with infectious diarrhea have changed during the last decade in Shanghai. METHODOLOGY The records of 29,210 patients with infectious diarrhea in the outpatient department of the Jinshan Hospital (Shanghai, China) between January 1998 and December 2013 were analyzed. RESULTS A total of 2,849 samples were positive for intes...

Acute gastroenteritis is a common infection among the children. The present study was conducted to study the bacterial pathogens in paediatric diarrhoeas and their antibiotic resistance pattern. Stool samples were collected between January 2012 to December 2012. A total of 118 patients with diarrhoea who were under five years of age. Stool samples were inoculated, isolated and identified using ...

BACKGROUND Stool cultures for Campylobacter, Salmonella and Shigella and/or Yersinia spp. are frequently ordered in critically ill patients with diarrhea. The aim of this study is to analyze the diagnostic yield in a large cohort of critically ill patients. Therefore, we performed a cohort study at the Department of Intensive Care Medicine of a University Hospital (11 ICUs). RESULTS From all ...

INTRODUCTION This study assessed the microbial quality of clay samples sold on two of the major Ghanaian markets. METHODS The study was a cross-sectional assessing the evaluation of processed clay and effects it has on the nutrition of the consumers in the political capital town of Ghana. The items for the examination was processed clay soil samples. RESULTS Staphylococcus spp and fecal col...

Introduction: Microbial contamination prediction through detecting the indicator bacteria in natural waters is the first health and environmental step for preventing the transmission of water-associated diseases. This study was designed to determine the correlation between Escherichia coli as the indicator bacterium, on the one hand, and Salmonella and Shigella Spp. As the pathogenic bacteria, ...

Gene clusters for biosynthesis of 24 of 34 basic O-antigen forms of Shigella spp. are identical or similar to those of the genetically closely related bacterium Escherichia coli. For 18 of these relatedness was confirmed chemically by elucidation of the O-antigen (O-polysaccharide) structures. In this work, structures of the six remaining O-antigens of E. coli O32, O53, O79, O105, O183 (all rel...