BACKGROUND Different methods have been studied for targeting drugs to the colon, such as pH-based, time dependent and bacterially degradable systems. However, due to variations in physiological conditions of patients, one system alone could not be completely reliable on colonic drug delivery. OBJECTIVES The aim of this study was preparation and evaluation of a novel colon-specific drug delive...

En la última década, políticos, analistas y periodistas han reactivado el concepto de Guerra Fría (GF) para aplicarlo como categoría analítica a situaciones del presente. La invasión Ucrania por Rusia en febrero 2022 ha puesto radicalmente actualidad Nueva (NGF) o Segunda (SGF). Nuestra investigación busca responder tres interrogantes fundamentales: 1. ¿en qué medida empleo analogía histórica G...

Cannabidiol (CBD) and cannabigerol (CBG) are two active pharmaceutical ingredients, derived from cannabis plant. In the present study, CBD CBG were formulated with polyvinyl(pyrrolidone) (PVP) Eudragit L-100, using electrohydrodynamic atomization (electrospinning). The produced fibers smooth uniform in shape, average fiber diameters range of 700–900 nm for PVP 1–5 μm L-100 fibers. encapsulation...

We study high-pT Higgs boson production in hadron collisions at one loop to order O(asGF 3 ). In particular, we investigate the process g1q( q̄)→q( q̄)1H , where q5u ,d ,c ,s , or b , for the CERN LHC ~a As514 TeV proton-proton collider!. Our results are compared to the O(as GF) and O(asGF) calculations. The associated production of a high-pT Higgs boson with a b quark or antiquark at O(asGF 3 ) ...

objective(s): in a new approach, following the development in metal oxide chemistry, the ibuprofen as low water soluble nonsteroidal anti-inflammatory drug diffused into synthetic sol-gel derived nano porous g-alumina by an impregnation method in order to increase the solubility and control the drug release in physiological environment. methods: sol-gel method was utilized for the fabrication o...

Many current sentence generators lack the ability to compute elliptical versions of coordinated clauses in accordance with the rules for Gapping, Forward and Backward Conjunction Reduction, and SGF (Subject Gap in clauses with Finite/Fronted verb). We describe a module (implemented in JAVA, with German and Dutch as target languages) that takes non-elliptical coordinated clauses as input and ret...

This thesis introduces concepts for learning expert human positional classifiers in the game of Go. While most studies in the field of Go focus on learning methods to find the best move, this thesis focuses on learning methods for evaluating the quality of Go stones in a position. A data set of 2,638 Go Tesuji problems has been created. For these problems expert human classifiers have been reco...

Three different human tumor lines in culture, a rhabdomyosarcoma, a bronchogenic carcinoma and a metastatic melanoma, release proteins (transforming growth factors, TGFs) into the medium that confer the transformed phenotype on untransformed fibroblasts. These proteins are acid and heat-stable; produce profound morphologic changes in rat and human fibroblasts; and enable normal anchorage-depend...

Cadaveric dissections and surgical observations have led to the description and clarification of the boundaries. blood supply, and nomenclature of the layers of the scalp. Special attention was directed to the layer of "loose connective tissue" that lies beneath the entire galea and above the cranial periosteum centrally, and the temporalis fascia laterally. It has been named the subgaleal fasc...