Ovarian neoplasms are relatively rare in childhood and adolescence; only 5% to 8% of the cases are of sex cord stromal origin. Granulosa cell tumors are a group of estrogen producing sex cord stromal tumors of the ovary. They occur in 95% of the cases in adults, and only about 5% of the cases, which differ in histologic characteristics, are of juvenile type. A 13-year-old girl is reported who p...

We aimed to investigate the expression and significance of Epstein-Barr virus-latent membrane protein 1 in human immunodeficiency virus-related diffuse large B-cell lymphomas. 22 cases lymphomas samples were collected. The control group consisted 7 non-human lymphomas, 6 virus-reactive hyperplasia virus. was detected by immunohistochemistry analyzed combination with clinicopathology characteris...

A 50-year-old peri-menopausal woman presented with hard palpable mass on her lower abdomen and anemia from heavy menstrual bleeding. Ultrasonography showed a 13×12 cm sized hypoechoic solid mass in pelvis and a 2.5×2 cm hypoechoic cystic mass in uterine endometrium. Abdomino-pelvic computed tomography revealed a hypodense pelvic mass without enhancement, suggesting a leiomyoma of intraligamenta...

the methanolic extracts of indigofera aspalathoides (meia) and wedelia calendulaceae (mewc) were evaluated for their anticancer activity against ehrlich ascites carcinoma (eac) in swiss albino mice. on day 1, the extract of indigofera aspalathoides at a dose of 250 and 500 mg/kg body weight and the extract of wedelia calendulaceae at a dose of 250 and 500 mg/kg body weight were administered ora...

exosomes, as a mediator of cell-to-cell transfer of genetic information, act an important role in intercommunication between tumor cells and their niche including fibroblasts, endothelial cells, adipocytes and monocytes. several studies have shown that tumor cells can influence their neighboring cells by releasing exosomes. these exosomes provide signaling cues for stimulation, activation, prol...

background: chemo-immunotherapy is one of the new achievements for treatment of cancer, by which the success of anti-cancer therapy can be increased. in vitro studies have been shown that arteether (are) induces apoptosis in tumor cells, but not in normal cells. objective: to investigate the cytotoxic and immunomodulatory properties of arteether in-vivo and in-vitro. methods: in this study, we ...

Background: Chemo-immunotherapy is one of the new achievements for treatment of cancer, by which the success of anti-cancer therapy can be increased. In vitro studies have been shown that Arteether (ARE) induces apoptosis in tumor cells, but not in normal cells. Objective: To investigate the cytotoxic and immunomodulatory properties of Arteether in-vivo and in-vitro. Methods: In this study, we ...

♦Corresponding Author: Kavita Mardi, MD, DNB 12-A, Type V Quarters, IAS Colony, Kasumpti, Shimla, H.P Tel: 9418063130 Email: [email protected] Introduction The sex cord-like variant of endometrioid adenocarcinoma is a rare tumor that histologically closely resembles the sex cord-stromal tumor of the ovaries.1 Despite its rarity, the correct histological diagnosis of the sex cord-like vari...

A 34-year-old man underwent left hemicastration for malignant unclassified sex cord gonadal stromal tumor. At 6 months pulmonary metastases developed and the patient received 3 courses of chemotherapy consisting of cisplatin, bleomycin and etoposide. A residual focus in the right lung was excised and proved to be viable tumor. He then received 2 adjuvant courses of cisplatin, etoposide and ifos...