PURPOSE To evaluate the visual system of patients suffering from type I or VI mucopolysaccharidosis (MPS) by recording the visual evoked cortical potential (VECP). METHODS Two patients with MPS VI and 2 patients with MPS I were tested before and after enzyme replacement therapy (ERT). A control group of 20 subjects was tested for statistical comparison. VECP was elicited by monocular stimulat...

Background: Leber congenital amaurosis (LCA) is a rare inherited retinal disease causing severe visual impairment in infancy. It has been reported that 9-15% of LCA cases have mutations in CRB1 gene. The complex of CRB1 protein with other associated proteins affects the determination of cell polarity, orientation, and morphogenesis of photoreceptors. Here, we report three novel pathogenic varia...

Background: Visual impairment is one of the independent risk factors for falling among the elderly. Functional disabilities caused by vision disorders are the most common problems affecting the quality of life in this population. Therefore, vision self-management program (VSM) may be helpful for patients in reducing impairment and improving the quality of life. Aim: The present study aimed to i...

purpose: to evaluate the preschool vision screening program coverage and to assess its validity indices including specificity, negative predictive value (npv), sensitivity and positive predictive value (ppv) and the frequency of treatment for visual impairment. methods: a sample of 906 six-year-old children signed up for primary school registration in the shahrood district (semnan, iran) were r...

OBJECTIVE To investigate and describe the prevalence and causes of blindness and moderate and severe visual impairment in older adults living in Uruguay. METHODS All individuals aged ≥ 50 years old living in randomly selected clusters were eligible to participate. In each census enumeration unit selected, 50 residents aged 50 years and older were chosen to participate in the study using compa...

OBJECTIVES To investigate the importance of vitamin A deficiency as a cause of childhood blindness and severe visual impairment (SVI) in India. DESIGN AND SETTING Cross sectional survey of children with visual acuity less than 6/60 in the better eye (SVI/blindness), attending 22 schools for the blind in nine states of India. MAIN OUTCOME MEASURE Proportion of children with blindness or SVI ...

Dear Editor, The recent report you published on the use of optical coherence tomography (OCT) to evaluate dengue was very interesting [1]. Rhee and Han [1] concluded that “Follow-up examination of individuals with dengue fever and associated visual impairment should involve the use of OCT to evaluate visual acuity and visual field change.” In fact, the ocular complications of dengue are typical...

BACKGROUND The northeastern region (NER) of India is geographically isolated and ethno-culturally different from the rest of the country. There is lacuna regarding the data on causes of blindness and severe visual impairment in children from this region. AIM To determine the causes of severe visual impairment and blindness amongst children from schools for the blind in the four states of NER ...