A brief historical review is presented of the development of bovine serum albumin as a standard for the determination of serum total protein. Bovine serum albumin is now available as a standard reference material from the National Bureau of Standards. Also reviewed is the present status of the immunoglobulin standards.

Objective: The objective of the study is to assess protein oxidation status and its correlation with antioxidant potential in serum during preeclampsia (PE). Materials Methods: A casecontrol was performed on 63 pregnant subjects (mean age = 30 tential serpreeclamptic 32 age-matched normotensive (control) women. Serum samples were analyzed for total protein, globulin, albumin, carbonyls (PCO), a...

Abstract Background Severe traumatic brain injury (TBI) is associated with blood–brain barrier (BBB) disruption and a subsequent neuroinflammatory process. We aimed to perform multiplex screening of enriched inflammatory proteins in blood cerebrospinal fluid (CSF) order study their role BBB disruption, neuroinflammation long-term functional outcome TBI patients healthy controls. Methods conduct...

Introduction Staphylococcus aureus seriously threatens human and animal health. IsdB137-361 of the iron surface determinant B protein (IsdB) from S. exhibits strong immunogenicity, but its immunoprotective effect is still to be further promoted. Because PEI-PLGA nanoparticles are generated by PEI conjugate with PLGA develop great potential as a novel immune adjuvant, immunogenicity likely stren...

Two hundred consecutive specimens received in this laboratory for "liver function tests" showed a wide range of abnormal protein concentrations. Calcium concentration correlated closely with albumin (r = 0.867) but less closely with total protein (r = 0.682). A simple formula for adjusting calcium concentration was derived from the regression equation of calcium on albumin. Adjusted calcium = c...

1. Experiments were carried out to test the hypothesis that there exists a special circulating fraction of plasma protein available for use by the tissues. 2. The changes in serum protein concentration after varying periods of fasting were followed in large numbers of individual rats. 3. Previous reports from this laboratory of a small initial drop in the total protein concentration of the seru...

Nucleocapsid (N) protein of infectious bronchitis virus (IBV), one of the viral structural proteins, inducesstrong antibody response in natural infection. In this study, a simple, recombinant N protein-based dot-blottest was developed to serologically examine chicken serum samples for the presence of IBV antibody.Initially, 72 serum samples were tested for the presence of IBV antibody using a c...

Changes were studied in the standard solubility curve of fresh serum proteins by alterations in pH, temperature, concentration of protein, and nature of the salt used for precipitation. The principal factor affecting the precipitation of protein fractions was a change in temperature. In order to investigate the proteins in their original states low temperatures are necessary. Protein fraction A...

Infusions of heterologous serum proteins large enough to replace the entire normal catabolic loss of the corresponding autologous proteins in the recipient rabbits caused increased rates of plasma protein catabolism, an increase in the size of the plasma protein pool and normal or even slightly increased rates of plasma protein synthesis. The principal proteins in these infusions were cataboliz...