SUMMARY OBJECTIVE: The aim of this retrospective study was to investigate the correlation transiently elevated postoperative serum cancer antigen 125 levels and prognosis in patients with non-small cell lung cancer. METHODS: A total 181 normal preoperative were statistically summarized study. RESULTS: Out analyzed patients, 22 (12.2%) showed elevation within one month after surgery. Serum level...

(-300 words text) summarize findings that are of interest to a relatively limited audience. Readersdesiringfuller details may obtain them by writing directly to the author(s) at the address given. Briefs dealing with procedure or instrumentation intercompari-sons,evaluations, or improvements(including kit applications) shouldbe sent to As is well known. the coenzyme pyridoxal 5'-phosphate (PU')...

Objective: Aging is a multifactorial phenomenon, which attribute to different diseases and abnormalities in living systems. Oxidative stress, which is an important factor in aging, exacerbates this process via different mechanisms. Crocin (CR), one of the active components of saffron showed strong antioxidant effects. In the present study, anti-aging property of crocin was investigated in mice....

Abstract Background and Aims Glomerulonephritis is one of the most common causes chronic kidney disease (CKD). Causes glomerular diseases include lupus nephritis (LN), focal segmental glomerulonephritis (FSGS) minimal change (MCD). The hallmark CKD renal fibrosis characterized by an imbalanced turnover extracellular matrix (ECM) components associated with increased inflammation. aim for this st...

Though the effects of acupuncture in atopic dermatitis have been proven in clinical studies, its mechanism remains unclear. In this study, we investigate the effectiveness and mechanism of action for acupuncture treatment on the LI11 meridian point for treatment of allergic contact dermatitis. BALB/c mice received 1-chloro-2,4-dinitrobenzene (DNCB) application to induce skin inflammation. Acupu...

OBJECTIVE Neutrophil elastase is secreted by neutrophils during activation and circulates in the plasma where it can play a role in inflammation and fibrosis. This study examines the role of neutrophil elastase in SSc, a systemic CTD that is typified by vascular dysfunction, tissue fibrosis and inflammation. METHODS Serum neutrophil elastase and α₁-anti-trypsin concentrations were assessed in...

OBJECTIVES Non-thyroidal illness syndrome (NTIS) is a form of hypothyroidism that occurs during illness. NTIS is characterized by low thyroid hormones (TH) level in the serum and tissues, with normal serum TSH levels that are considered "inappropriately" normal. The mechanisms responsible for a lack of increase in serum TSH during NTIS are unknown. However, a decreased expression of hypothalami...

Objectives: Analyzing the trend in the serum inflammatory cytokines levels in a historical cohort of patients treated with combination of chloroquine and methimazole. Material and methods: We analyzed the pro-inflammatory serum cytokines level [Interleukin-6(IL-6), Tumor Necrosis Factor alpha (TNF-α), Interleukin 1 alpha (IL-1 α) and Interferon gamma (INF-γ)] in the stored blood samples of 22 p...

OBJECTIVE Urocortin 1 (UCN1) has vasodilator, diuretic, and natriuretic effects, and its expression increases in heart failure (HF). Adrenomedullin (ADM) increases cardiac output and lowers blood pressure in healthy men and in patients with heart failure. The aim of the study was to determine UCN1 and ADM levels in patients with HF, to evaluate the relationship of UCN1 and ADM with various clin...