نتایج جستجو برای: serum icam

تعداد نتایج: 310670  

Journal: :Tobacco Induced Diseases 2002
RM Palmer RF Wilson PY Coward DA Scott

BACKGROUND IGF-1 and the major serum IGF-1 binding protein, IGFBP-3, are under extensive investigation as potential prognostic markers of specific malignancies and vascular diseases. However, there is conflicting evidence that tobacco smoking may influence systemic concentrations of IGF-1 and IGFBP-3. SUBJECTS AND METHODS Serum concentrations of IGF-1 and IGFBP-3 were measured in 20 smokers a...

Journal: :Anticancer research 2004
K N Syrigos E Salgami A J Karayiannakis N Katirtzoglou E Sekara P Roussou

BACKGROUND Cell adhesion may play a pivotal role in the development, progression and metastasis of solid malignancies. We evaluated the serum concentration of four adhesion molecules and their prognostic significance in patients with Hodgkin's Disease (HD). PATIENTS AND METHODS Serum samples from 20 HD patients were collected at diagnosis, after 3 cycles of chemotherapy and at completion of t...

2016
Boda Zhou Chuan Ren Lingyun Zu Lemin Zheng Lijun Guo Wei Gao

Migration inhibitory factor (MIF) has been shown to be critical in the pathology of early artherosclerosis; this article aim to investigate the plasma levels of MIF in hypertension plus hyperlipidemia patients.A total of 39 hypertension plus hyperlipidemia patients without any previous treatment were enrolled (HTN-HLP). Twenty-five healthy subjects were enrolled as the healthy control group (HE...

2013
Hisham Saleh Ibrahim Effat Omar Gabrielle Ruth Anisah Froemming Harbindar Jeet Singh

Raised leptin levels have been reported in the placentae and serum of women with elevated blood pressure and proteinuria during pregnancy. The role of leptin in this however remains unknown. This study investigates the effect of leptin administration on systolic blood pressure (SBP) and proteinuria and serum markers of endothelial activation during pregnancy in Sprague Dawley rats. From day 1 o...

2016
Shuntaro Maruyama Tomohito Gohda Yusuke Suzuki Hitoshi Suzuki Yuji Sonoda Saki Ichikawa Zi Li Maki Murakoshi Satoshi Horikoshi Yasuhiko Tomino

BACKGROUND IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide. Tonsillectomy plus steroid pulse therapy has been able to induce clinical remission in early-stage IgAN. However, its possible effect on systemic and local cytokines and tubular markers has not been fully investigated. METHODS We obtained serum and urine samples from 38 patients just before rena...

2007
Yutaro Shiota fames G. Wilson Masaomi Marukawa Tetsuya Ono Masaro Kaji

Previous studies have suggested that intercellular ad¬ hesion molecule 1 (ICAM-1, CD54) may be involved in the pathogenesis ofasthma. In addition, a soluble form of ICAM-1 (sICAM-1) has been detected in increased concentrations in the sera of patients with certain in¬ flammatory conditions. To determine whether bron¬ chial asthma is associated with increased levels of sICAM-1 in serum and to as...

2015
Shiro Koizume Yohei Miyagi

The tumor microenvironment is generally hypoxic because of the limited oxygen supply from inefficient or insufficient vasculature. Hypoxic tumor tissues are also poorly supplied with serum components. We have previously demonstrated that expression of the FVII gene is induced in response to hypoxia in ovarian clear cell carcinoma (CCC) cells. This gene activation is synergistically enhanced whe...

2014
Gang Li Xiao-wei Wu Wei-hua Lu Rong Ai Fang Chen Zhong-zhi Tang

BACKGROUND Gamma-glutamyl transpeptidase (GGT) is now considered to be one of the risk factors for cardiovascular disease. However, whether statins can alter GGT levels in arterial atheromatous plaque has not yet been studied. Therefore, the aim of this study is to determine whether statins can effectively decrease the expression of GGT in arterial atheromatous plaques. METHODS We randomly di...

Journal: :Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2006
Petr Nachtigal Gabriela Jamborova Nada Pospisilova Katerina Pospechova Dagmar Solichova Petr Zdansky Vladimir Semecky

PURPOSE Atherosclerosis is a progressive process that initially involves endothelial dysfunction. We investigated the effects of atorvastatin on both lipid parameters, and VCAM-1 and ICAM-1 expression in apoE-deficient or wild type C57BL/6J mice. METHODS The C57BL/6J mice were fed with either chow or an atherogenic diet for 12 weeks. Male apoE-deficient mice were fed with the chow diet for 12...

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