BACKGROUND Pneumonia is the leading cause of childhood death in the developing world. Higher-quality etiological data are required to reduce this mortality burden. METHODS We conducted a case-control study of pneumonia etiology among children aged 1-59 months in rural Kenya. Case patients were hospitalized with World Health Organization-defined severe pneumonia (SP) or very severe pneumonia (...

Background and ObjectivePresented is a case of 28-year-old female, who was diagnosed with presumed COVID-19 (SARS-CoV-2) the sequelae her bilateral conjunctivitis. Since December 2019, presence severe acute respiratory syndrome has swept worldwide, infecting over 170 million to date counting. It been discovered that virus can make its way eyes due an abundance human angiotensin-converting enzym...

In the present study, serologic data were compared with data obtained by capillary PCR to establish the efficacy of capillary PCR for the determination of Mycoplasma infection in samples obtained from throat swabs, bronchoalveolar lavage fluids (BALF), and sputum of patients with Mycoplasma pneumonia. We performed PCR analysis for Mycoplasma DNA on a total of 325 samples from 197 patients with ...

BACKGROUND Trachoma, caused by ocular infection with Chlamydia trachomatis, is hyperendemic on the Bijagós Archipelago of Guinea Bissau. An understanding of the risk factors associated with active trachoma and infection on these remote and isolated islands, which are atypical of trachoma-endemic environments described elsewhere, is crucial to the implementation of trachoma elimination strategie...

PURPOSE To test the efficiency of locally administrated tresperimus in experimental autoimmune uveoretinitis (EAU). METHODS EAU was induced in Lewis rats by S-antigen (S-Ag) immunization. Three intravitreal injections of tresperimus (prevention or prevention/treatment protocols) were performed at different time points after immunization. The pharmacokinetics of tresperimus was evaluated in th...

Syphilis diagnosis is based on clinical observation, serological analysis, and dark-field microscopy (DFM) detection of Treponema pallidum subsp. pallidum, the etiological agent of syphilis, in skin ulcers. We performed a nested PCR (nPCR) assay specifically amplifying the tpp47 gene of T. pallidum from swab and blood specimens. We studied a cohort of 294 patients with suspected syphilis and 35...

BACKGROUND Associations between repeated ocular infections with Chlamydia trachomatis in childhood and conjunctival scarring in adulthood are well established. Trachomatous scarring (TS) in children has also been observed in hyper-endemic areas, but data are scant regarding childhood scarring in areas where trachoma has been reduced to hypo-endemic levels. METHODS/PRINCIPLE FINDINGS In this c...

conjunctivitis This condition is manifested as congestion or oedema (chemosis) of the conjunctiva. It may be accompanied by an ocular discharge. Secondary conjunctivitis may occur with other ocular conditions, such as uveitis and glaucoma. In cats, conjunctivitis is frequently caused by an infectious agent, and multiple agents may be involved. Resident ocular bacterial flora is present; therefo...

AIMS To report the clinicopathological characteristics of patients with ocular adnexal marginal zone B cell lymphoma (MZBL) with IgG4-positive plasma cells. METHODS 114 biopsy samples of ocular adnexal MZBLs were analysed. MZBLs with IgG4-positive plasma cells were included when the IgG4:IgG ratio was >40% (IgG4-related group). The serum levels of each subclass of immunoglobulins and soluble ...

the effect of genotype and sex of nigerian indigenous chickens (dwarf, fulani ecotypes, neck, frizzle and normal feathered) on blood serum electrolytes and biochemical parameters were investigated using 40 chickens. the collected data were subjected to analysis via a 2 way anova. the results revealed serum levels of sodium, potassium, chloride, uric acid, glucose, total protein, creatinin, albu...