albumin has a fundamental role in human body. its main tasks in blood are to regulate osmotic blood pressure, maintaining the ph, and transporting metabolites and drugs throughout the vascular system.  pharmacological studies of the interaction of drugs on hsa are important due to structural and functional changes of this vital protein; thus, here in this research the effect of valproate as a c...

context maternal serum human chorionic gonadotropin (hcg) and alpha fetal protein (afp) were originally introduced to detect trisomy 21 and neural tube defects. however, in the absence of aneuploidy or neural tube defects, mid-trimester maternal serum hcg and/or maternal serum afp associated with adverse pregnancy outcomes. pregnancies with unexplained mid-trimester elevation in maternal serum ...

background the current organ shortage has prompted the use of marginal organs. we conducted this retrospective study to present our experience with transplanting deceased donor livers with elevated levels of serum transaminases and to explain whether elevated levels of serum transaminases in donors affect allograft function and survival of the recipients. methods data of deceased donor livers a...

conclusions cornus mas fruit extract effect may be due to including some antioxidant components, which caused membrane stabilizing and normalization of fluctuated biochemical profiles induced by ccl4 exposure. our results validated the traditional use of cornus mas in the treatment of liver disorders. results oral administration of cornus mas fruits extract to rats for 14 days provided a signif...

objective: breath holding spells, very often misinterpreted as epileptic seizures, are most common in children aged 6 months to 6 years of age. in this investigation, we sought to prospectively document the natural history of breath holding spells (bhs) among children with cyanotic, pallid and mixed type bhs referred for neurological consultation. materials & methods: this was a cross-sectional...

introduction: one of the most common pathologies in neonates is hyperbilirubinemia, which is a good marker for damage to the central nervous system. the sensitivity of the auditory system to bilirubin has been previously documented, with much discrepancy in its effects on auditory brainstem response results. thus the objective of this study was to evaluate the effects of hyperbilirubinemia on a...

objective: oxidative stress is a serious complication in diabetic patients. black tea and also sour tea contained some flavonoids with antioxidant properties and may be helpful in prevention of lipid oxidation. the aim of this study was to compare the effects of sour tea and black tea on in-vitro copper induced serum lipids oxidizability in diabetic patients. materials and methods: in this sequ...

human serum albumin (hsa) is the most abundant protein constituent of blood plasma. this protein consists of a single polypeptide chain of 585 amino acid residues, which has many important physiological functions. hsa can bind and carry many drugs, including anticoagulants, tranquilizers, and general anesthetics. some technique such as: fluorescence spectroscopy, three-dimensional fluorescence ...