To assess the influence of donor, environment, and logistical factors on the results of virological testing of blood samples from cornea donors.Data from 670 consecutive cornea donors were analyzed retrospectively. Logistic regression analysis was used to assess the influence of different factors on the results of virological testing of blood samples from cornea donors.The mean annual rate of d...

AIMS To determine how the microbiology laboratories of one region process serological requests from patients with suspected infectious illness, referred to as "clinical syndrome" type patients in this study; to consider areas where improvement in the associated serology service could be made. METHODS A prospective two month collection of data on all serological requests from patients with sus...

the last two decades have seen a massive growth in the application of dna technology in histocompatibility and immunogenetics. this review summarises the history and application of dna methods in this area.

BACKGROUND Diagnosis of community-acquired pneumonia (CAP) caused by Mycoplasma pneumoniae (Mp) in children has been hampered by difficulty in obtaining convalescent serum and time constraints. In this study, the two diagnostic assays that targeted respectively on Mp-antibody and Mp-DNA were retrospectively investigated. METHODS A total of 3146 children were clinically diagnosed to have CAP a...

BACKGROUND Chagas disease affects mainly poor populations in Latin America. This review assesses the evidence on the independent risk of cardiovascular events associated with positive Chagas serology. METHODS We searched for studies using the following outcomes: death, stroke, new onset heart failure, heart failure hospitalization or evidence of left ventricular dysfunction. Studies comparing...

Culture of the exudate revealed Staphylococcus aureus and Streptococcus equisimilis. Radiographs of the chest, foot, and ankle were normal. Serology showed evidence of past infection with hepatitis B virus but was negative for human immunodeficiency virus. Other laboratory tests, including complete blood count, coagulation studies, biochemistry, liver and kidney function tests, and serology, we...

OBJECTIVE The frequent occurrence of inconclusive serology in blood banks and the absence of a gold standard test for Chagas'disease led us to examine the efficacy of the blood culture test and five commercial tests (ELISA, IIF, HAI, c-ELISA, rec-ELISA) used in screening blood donors for Chagas disease, as well as to investigate the prevalence of Trypanosoma cruzi infection among donors with in...

OBJECTIVES/HYPOTHESIS Epstein-Barr virus (EBV) infection is a potential precursor of post-transplantation lymphoproliferative disorder (PTLD) in the pediatric transplant patient. Positron-emission tomography (PET) imaging is increasingly utilized in this population to monitor for neoplasia and PTLD. We assess the association between EBV serum titers and Waldeyer's ring and cervical lymph node P...

Culture of the exudate revealed Staphylococcus aureus and Streptococcus equisimilis. Radiographs of the chest, foot, and ankle were normal. Serology showed evidence of past infection with hepatitis B virus but was negative for human immunodeficiency virus. Other laboratory tests, including complete blood count, coagulation studies, biochemistry, liver and kidney function tests, and serology, we...

I F A SERUM contains a gamma globulin which will react with ( agglutinate, hemolyze or sens tize ) certain enetically well-defined red blood cells but not others, it is said to possess an antibody and the antibody is said to be specific for a certain property of the red cells. Thus the specificity of an antibody depends on this selective reactivity. This is often difficult to demonstrate if the...