Hemoglobin oxygen saturation in superior vena cava (ScvO(2)) is used as a parameter to guide hemodynamic management in shock patients and it can be continuously read through a central venous catheter equipped with a fiberoptic spectrophotometric probe (Edwards PreSep catheter) connected to a specific monitor (Edwards Vigileo). We report of an episode of erroneous ScvO(2) reading by this technol...

Blood components are indicated in a wide variety of disease states. Although most transfusion therapies are administered uneventfully, there are a number of potential adverse transfusion reactions, some of which can assume serious dimensions. These reactions could occur during or even days after a transfusion. A brief description of the adverse effects of transfusion therapy has been outlined i...

Many medical institutions in Korea have recently been performing an antibody screening test as one of the essential elements of a pre-transfusion test. The Di(a) antigen is well known as one of the antigens with low incidence among Caucasians; however, it has been discovered with a relatively higher incidence among Mongoloid populations. The frequency of the Di(a) antigen among the Korean popul...

This cross-sectional study aimed to evaluate the knowledge of 316 nurses in a Malaysian public hospital regarding blood transfusion procedures. Convenience sampling was used select involved patient care. Data collection employed validated questionnaire with 33 questions across four sections. Descriptive analysis using SPSS revealed gaps, particularly and adverse reaction management. Findings sh...

Patients with autoimmune haemolytic anaemia (AIHA) frequently have anaemia of sufficient severity as to require a blood transfusion. However, it is impossible to find compatible blood when, as is frequently the case, the autoantibody in the patient's serum reacts with all normal red blood cells. Further, the autoantibody may mask the presence of a red cell alloantibody capable of causing a haem...

Psittacosis is a zoonotic infectious disease causing communityacquired pneumonia. Septic shock and respiratory failure can develop. The symptoms, diagnosis, transmission and treatment of psittacosis are discussed. In the described cases, especially polymerase chain reaction has shown to be a promising tool in diagnosing the disease. Physicians awareness might be accelerated to ensure rapid trea...

INTRODUCTION Recent evidence suggests that early, aggressive resuscitation in patients with septic shock reduces mortality. The objective of this survey was to characterize reported resuscitation practices of Canadian physicians caring for adult critically ill patients with early septic shock. METHODS A scenario-based self-administered national survey was sent out to Canadian critical care ph...

Sterile abscess, pleuritis, and pancreatitis give a clinical reaction in the experimental animal very like the same acute inflammatory processes due to bacterial activity, provided the bacterial agents are limited to the initial location. The curve of urinary nitrogen excretion in the fasting dog shows the same precipitous and sustained rise in sterile and bacterial inflammatory reactions. This...

Background: Patients with thalassemia major require frequent blood transfusions. Blood transfusion can lead to the adverse reactions. Reporting and evaluating the transfusion reactions are among the goals of implementing the hemovigilance system to improve blood recipients’ safety. This study aimed to compare the transfusion reactions in the thalassemia patients before and after implementation ...

Delayed hemolytic transfusion reaction (DHTR), a life-threatening transfusion complication in sickle cell disease (SCD), is characterized by a marked hemoglobin drop with destruction of both transfused and autologous red blood cells (RBCs) and exacerbation of SCD symptoms. One mechanism of RBCs destruction is auto-antibody production secondary to transfusion. As rituximab specifically targets c...