Sepsis affects millions of people worldwide each year. It occurs when a normal human immune response to a bacterial, viral or fungal infection becomes dysfunctional and triggers widespread inflammation that results in severe tissue damage that leads to organ failure, shock, and death. Sepsis, requires immediate treatment and has a high readmission rate for survivors. It is also one of the most ...

Background: The management of neonatal sepsis especially in developing countries is problematic.  There is no single reliable marker of infection available at the present.  C-reactive protein (CRP) has long been used as a marker of infection. Serial measurements of CRP are recommended as a guide for duration of antibiotic therapy. Objective: To evaluate the serial CRP measurement as a guideline...

Background: Sepsis is regarded as a critical clinical status in neonates. Since blood culture is a time-consuming method, the present study was conducted to investigate the serum level of Ferritin, Procalcitonin, and CRP in the peripheral blood of term neonates suspected with sepsis to have a quicker diagnosis for the disease. Methods: In the pres...

introduction: although significant development in the field of medicine is achieved, sepsis is still a major issue threatening humans’ lives. this study was aimed to audit the management of severe sepsis and septic shock patients in emergency department (ed) according to the present standard guidelines. method: this is a prospective audit on approaching adult septic patients who were admitted t...

procalcitonin (pct) is a precursor peptide for the hormone calcitonin and is frequently increased in overt sepsis. the aim of this study was to test diagnostic accuracy of procalcitonin among patients with positive systemic inflammatory response syndrome (sirs) in identifying sepsis. in this cross sectional study, from 563 patients with positive sirs admitted through the emergency department of...

background and objectives: mortality is highly variable within population of cultured fish due to virulent bacteria causing fish septicemia. the use of nano-silver marine fungal chitosan as antibiotic synergisers could be an alternative in the treatment of sepsis fish pathogens. materials and methods: different bulk chitosan solutions were prepared from the mycelia of four marine fungi ( asperg...

objective: to analyze the trend in maternal mortality ratio in a tertiary care centre and the effect of various maternity schemes on it. materials and methods:  retrospective analysis of all maternal deaths occurring in the guru gobind singh medical college & hospital, faridkot, punjab, india was done from jan 2010 to dec 2012. every maternal death was scrutinized from various aspects like dire...

background: myocardial dysfunction is one of the major complications in patients with sepsis where there is a relationship between the blood level of cytokines and the onset of myocardial depression. in many cases of sepsis, the presence of lipopolysaccharide (lps) has been established. lps binding protein (lbp) bound endotoxin is recognized by cd14/toll-like receptor-4 (tlr4) complexes in inna...

INTRODUCTION Sepsis and severe sepsis are associated with high hospital mortality. Little is known about the occurrence of sepsis in general hospital populations. The goal of the present study was to reveal the epidemiology of sepsis in Norwegian hospitals over 1 year. METHODS Patients admitted to all Norwegian hospitals during 1999 (n = 700,107) were analyzed by searching the database of the...