This research aims to simulate a gravity flow fractionation—the process to fractionate erythrocytes through gravitational field using ANSYS simulation software. A particular microfluidic channel was designed as a separation device. The gravitational equilibrium conditions of the erythrocytes and gravitational field as the parameters were chosen, then deriving the erythrocytes’ path through nume...

Dielectrophoretic field-flow-fractionation (DEP-FFF) was applied to several clinically relevant cell separation problems, including the purging of human breast cancer cells from normal T-lymphocytes and from CD34+ hematopoietic stem cells, the separation of the major leukocyte subpopulations, and the enrichment of leukocytes from blood. Cell separations were achieved in a thin chamber equipped ...

Continuous hydrolysis of an active pharmaceutical ingredient intermediate, and subsequent liquid−liquid (L-L) separation of the resulting organic and aqueous phases, have been achieved using a simple PTFE tube reactor connected to a miniscale hydrophobic membrane separator. An alkoxide product, obtained in continuous mode by a Grignard reaction in THF, reacted with acidic water to produce parti...

Numerical results are presented for the shock-boundary layer interactions in a hypersonic flow over a sharp leading edge compression corner. In this study, a second- order Godunov type scheme based on solving a Generalized Riemann Problem (GRP) at each cell interface is used to solve thin shear layer approximation of laminar Navier-Stokes (N-S) equations. The calculated flow-field shows general...

We investigate experimentally the causes of jet plume instability and enhanced mixing observed in the exhaust of shock-containing convergent-divergent nozzles. Key features of the internal flow are the separation shock, separation shear layers, and pattern of alternating expansion and compression waves downstream of the shock. We focus on two possible reasons for this instability—the motion of ...

This work considers the instability of the jet plume from an overexpanded, shockcontaining convergent-divergent nozzle and attempts to correlate this instability to internal shock-induced separation phenomena. Time resolved wall pressure measurements and Pitot measurements are used as primary diagnostics. For the conditions of this study flow separation is asymmetric resulting in a large separa...

Shock-boundary layer interaction (SBLI) is a kind of problem which is frequently met in supersonic engine inlet flow and external flow. A detail study on mechanism of reduction of shock induced flow separation by MVG is carried out by high order implicit large eddy simulation (LES). To generate the fully developed turbulent flow, a series of turbulent profiles are given by previous DNS simulati...

the monolithic catalytic converter is still the main pollution control device for modern vehicles in order to reach the ever-increasing legislative demands for low emission standards. the catalytic converters require a large expansion from the exhaust pipe to the front face of the monolith. unfortunately, packaging constraints often do not permit the use of long diffusers. hence, flow separatio...

Assurance of information flow security by formal methods is mandated in security certification of separation kernels. As an industrial standard for separation kernels, ARINC 653 has been complied with by mainstream separation kernels. Security of functionalities defined in ARINC 653 is thus very important for the development and certification of separation kernels. This paper presents the first...

A gas permeation model (Coupling Model) has been developed which has the flexibility to be used for different membrane module configurations. The aim of this work is to predict the performance of a single stage gas separation process using membranes and provide a comprehensive description of process parameters like flow rates, composition, stage cut and stream pressure. The significant feature ...