BACKGROUND The use of niacin in the treatment of dyslipidemias is limited by the common side effect of cutaneous vasodilation, commonly termed flushing. Flushing is thought to be due to release of the vasodilatory prostanoids prostaglandin D2 (PGD2) and prostaglandin E2 from arachidonic acid metabolism through the cyclooxygenase pathway. Arachidonic acid is also metabolized by the cytochrome P4...

Two experiments were conducted, aimed at improving the practicability of the method for transcervical embryo collection in Boer goats described by Pereira et al. [Pereira, R.J.T.A., Sohnrey, B., Holtz, W., 1998. J. Anim. Sci. 76, 360-363]. Invention of a hammock-like restraining device, use of a wider-bore flushing catheter and a modified flushing mode contributed toward this end. The importanc...

Researchers have independently documented the effects of land use on rivers and threats to river management institutions, but the relationship between changes in institutional context and river condition is not well described. This study assesses the connections between resource management institutions, land use, and rivers by integrating social science, geospatial analysis, and geomorphology. ...

The experimental approach has been used to study successfully the relationship between the polymorphism of aldehyde dehydrogenase 2 and the flushing syndrome. In the present study, a probabilistic approach was used to analyse this relationship. Using cross-impact analysis and experimental data, the probability of the occurrence of flushing, the extent by which ALDH2*2/*2 enhances flushing more ...

BACKGROUND Flushing is generally considered to be the primary symptom of menopause and is typically the most common complaint in menopausal women. Although flushing poses no danger to a woman's health, it decreases the quality of life. Thus, the purpose of this study was to determine the effect of lavender aromatherapy on menopause flushing. METHODS This double-blinded crossover clinical tria...

flushing is a condition with episodic attacks of redness of the skin with a sensation of warmth or burning, this disease causes emotional and functional problems in patients. there is various treatments for this condition; one of them is the use of botulinum toxin-a (bta). in this prospective pilot study we studied the effect of botulinum toxin-a (bta) effect on dlqi of patients with facial flu...

Encouraging sustainable water use is a critical endeavor in addressing issues associated with shortand long-term droughts. Toilets account for up to 26.7% of indoor household water use. Therefore substantial opportunity exists to conserve water via reduced flushing after urination at home. Here, we use an online survey (N 1⁄4 1008) to identify barriers to reduced flushing. The majority of parti...

A modelling methodology using a leachate source term has been produced for estimating the timescales for achieving environmental equilibrium status for landfilled waste. Results are reported as the period of active management required for modelled scenarios of non-flushed and flushed sites for a range of pre-filling treatments. The base scenario against which results were evaluated was raw muni...