نتایج جستجو برای: second exon of bula
تعداد نتایج: 21187492 فیلتر نتایج به سال:
Background It is unknown whether the outcomes of second-line pemetrexed-carboplatin chemotherapy administered after progression on gefitinib are dependent on type of EGFR mutation present at baseline. Method Adult non-small-cell lung cancer patients, with exon 19 deletion or exon 21 L858R mutation, who progressed on gefitinib and received pemetrexed-carboplatin chemotherapy were selected for ...
abstract the variables affecting the nature of reading comprehension can be classified into two general categories: reader’s variables, and text variables (alderson, 2000). despite the wave of research on vocabulary knowledge as reader’s variable, the role of this knowledge in c-test as a text-dependent test and its interaction with lexical cohesion of the test as a text feature has remained a...
having conducted the experiment and analysed the data, the researcher computed the groups mean scores and variances for the test relating to the research question. as the final atep, a t-test was conodonted for the hypothesis. as noted earlier, the significance level was determined at .05 and .01 respectively. the observed t-value was higher than the critical t-value at. 5 and .01 levels. conse...
چکیده به منظور بررسی اثر تنوع گیاهی و نوع منبع تغذیه ای بر تنوع و تراکم علفهای هرز و حشرات، کارایی مصرف نهاده ها ( نور، آب، عناصر غذایی) و عملکرد و خصوصیات کیفی چند گونه زراعی، آزمایشی به صورت کرتهای خردشده بر پایه طرح بلوکهای کامل تصادفی با سه تکرار در دو سال زراعی 1385-1384 و 1386-1385 در مزرعه تحقیقاتی دانشکده کشاورزی دانشگاه فردوسی مشهد به اجرا درآمد. تیمارهای مورد بررسی دو منبع کود دامی و...
background: patients with diabetes mellitus type ii suffer from hyperglycemia because they are not able to use the insulin that they produce, often due to inadequate function of insulin receptors. there are some evidences that this deficiency is inherited in a dominant autosomal manner and leads to the malfunction of the pancreatic beta cells resulting in insulin excretion disorders. in this st...
background: leishmaniasis is a protozoan disease cause by leishmania genus. anthroponotic and zoonotic cutaneous leishmaniasis are endemic in iran. the aim of this study was to identify the causative agent of cutaneous leishmaniasis by mini-exon gene in five regions of khuzestan province, southwest of iran. methods: from 2007 to 2008 in this cross-sectional study, cutaneous samples were collec...
Immortalization of primary cells is an early and important event in multistep tumorigenesis and is itself a multistep process. Adenovirus E1A 12S encodes an oncoprotein that can rescue cells from senescence and overcome apoptosis, leading to their immortalization. Five regions of 12S, located in both exons, are required for immortalization. Two regions in the first exon are necessary to activat...
Background & Aim: Mutations in c-kit gene cause autonomously proliferation of leukemic cells with an unfavorable prognosis.These mutations including exon 8 deletion and insertion in the fifth extracellular Ig-like domain and exon 17 point mutation in tyrosine kinase domain of c-kit receptors are important in acute myeloid leukemia. The aim of this study was to set up molecular diagnosis and ...
The exon-junction complex (EJC) deposited on a newly spliced mRNA plays an important role in subsequent mRNA metabolic events. Here we show that an EJC core heterodimer, Y14/Magoh, specifically associates with mRNA-degradation factors, including the mRNA-decapping complex and exoribonucleases, whereas another core factor, eIF4AIII/MLN51, does not. We also demonstrate that Y14 interacts directly...
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