Standard dialyzer membranes, designed for diffusive clearance, do not effectively clear protein-bound uremic toxins, such as indoxyl sulfate (IS). To increase toxins removal, absorbents require a high specific surface area to achieve effective size-coupling removal of target toxins. However, the toxicity molecule is necessarily determined by size alone. As proof concept, we report on an electro...

SelB is a specialized translation elongation factor that delivers selenocysteyl-tRNA(Sec) (Sec-tRNA(Sec)) to the ribosome. Here we show that Sec-tRNA(Sec) binds to SelB.GTP with an extraordinary high affinity (K(d) = 0.2 pm). The tight binding is driven enthalpically and involves the net formation of four ion pairs, three of which may involve the Sec residue. The dissociation of tRNA from the t...

the distribution of gallium(b) and indium (b) between hydrochloric or sulphuric acid solution with sec-nonylphenoxy acetic acid(ca-100) in kerosene has been investigated under various conditions. ca-100 is a new organocarboxylic extractant, which has been shown to be efficient for gallium(b) and indium(b) whereas germanium(c), which was not extracted. the extraction system is studied as a funct...