Forty-three deaths were recorded among pigs fed boiled cassava meal at a private piggery over a period of two years. There were signs of sudden death in some cases with blood exuding from the external nares, vomiting, muscular weakness and pain or reluctance to move, emaciation, and stunted growth. The necropsy lesions included skeletal and cardiac muscle degeneration and necrosis, icterus, hep...

Melicope glabra­ (Blume) T. G. Hartley is a plant of Rutaceae family. The present study aimed to evaluate the in vivo hypoglycemic effect M. glabra leaves extract on diabetic rats and identify its bioactive components. induction diabetes Sprague-Dawley was done by combination high-fat diet low-dose streptozotocin injection. extracts standard sitagliptin were orally administered once daily for 2...

The chromatography fractionation of the hexane, chloroform and ethyl acetate extracts from the leaves and stems of Rourea doniana Baker, Connaraceae, resulted in the isolation of five triterpenes (lupeol, lupenone, α-amyrenone, β-amyrenone, and taraxerol), a flavonol (7,4’-dimethylkaempferol), a coumarin (scopoletin) and four phytosteroids (β-sitosterol, stigmasterol, β-sitosteryl-3-Oβ-D-glucop...

Previous report showed the high potent antiproliferative effect of the methanolic part extracted from the aerial parts of Pouzolzia indica on NB4 and HT93A acute leukemic cell lines with the IC50 values of 28.5 and 49.8  μ g/mL, respectively. The bioassay-guided fractionation of the methanolic part gave 5 fractions, that is, FFI-FFV. FFII, FFIII, and FFIV inhibited the above leukemic cell lines...

Coumarins belong to an important class of plant secondary metabolites. Feruloyl-CoA 6'-hydroxylase (F6'H), a 2-oxoglutarate dependent dioxygenase (2OGD), catalyzes a pivotal step in the biosynthesis of a simple coumarin scopoletin. In this study, we determined the 3-dimensional structure of the F6'H1 apo enzyme by X-ray crystallography. It is the first reported structure of a 2OGD enzyme involv...

Morinda citrifolia L., commonly known as noni, is a growing global commodity. As such , there is a need for rapid and inexpensive identity tests of noni fruit and leaf products. Thin Layer Chromatography (TLC) methods w ere developed for the identification of deacetylasperulosidic acid in noni fruit and leaf products. TLC methods were also developed for the identification of scopoletin in noni ...

Priya Shah, K Pundarikakshudu, Kinjal Patel and Maitreyi Zaveri Author informationArticle notesCopyright License information K. B. Institute of Pharmaceutical Education Research, Kadi Sarva Vishwavidyalaya, Gandhinagar, Gujarat, INDIA Department Pharmacognosy, L. J. Pharmacy, University, Sarkhej, Ahmedabad, Raval College Shertha,