Scintigraphic techniques can measure sequentially gastric emptying, small bowel transit, and colonic transit in humans, and comparable methods for experimental studies in animals would be useful. We developed such a method in dogs and examined the effects of prokinetic drugs on regional transit. Two isotopes were given to fasting dogs. Polystyrene pellets labeled with99mTc were mixed in a can o...

UNLABELLED In this case report, we present a 70 year old female patient who had recieved Leech therapy (hirudotherapy) on her leg without informing referring physician. In dynamic bone scintigraphy there was increased perfusion and hyperemia in her left ankle and leg, also in late static images moderate increased uptake was seen in soft tissue region and at the fracture site of ankle. We learne...

We compared 76 99mTc-DISIDA hepatobiliary studies with corresponding liver biopsies in 36 liver transplant patients to determine the histopathologic abnormalities that corresponded to scintigraphic abnormalities in uptake and excretion. Uptake was judged normal if the cardiac blood pool was barely visible or invisible on the ten minute image. Excretion was judged normal if images subsequent to ...

Radionuclide Tc99m DTPA (Diethylenetriaminepenta Acetic Acid) renal imaging is being used to assist in the evaluation of overall GFR, the intra-renal transit time, the cortical transit time, response to frusimide injection, diagnosis of ATN and rejection in renal transplant cases. A study was conducted at PINSTECH in order to prepare DTPA kit locally and evaluate the labeling efficiency as well...

The aim of this study is to investigate the use of mathematical morphology for the determination of left ventricular contours in scintigraphic images using multigated radionuclide angiography. We have developed a completely automatic method that first restores the image with a Wiener filter, then finds the region where the left ventricle is contained, and finally segments the left ventricle con...

Standard oesophageal scintigraphic techniques using 99mTc-colloids rarely identify oesophageal mucosal damage. Sucralfate can be labelled with 99mTc for the detection of oesophageal mucosal ulceration. This method uses two separate supine swallows of 10 MBq 99mTc-colloid in 10 ml, followed by a single supine swallow of 30 MBq 99mTc-sucralfate. The data are processed to give time-activity curves...

A complete Bayesian framework for Principal Component Analysis (PCA) is proposed in this paper. Previous model-based approaches to PCA were usually based on a factor analysis model with isotropic Gaussian noise. This model does not impose orthogonality constraints, contrary to PCA. In this paper, we propose a new model with orthogonality restrictions, and develop its approximate Bayesian soluti...

OBJECTIVE To determine the usefulness of 99mtechnetium (99mTc) immunoglobulin scintigraphy (99mTc IgG) in rheumatoid arthritis (RA) and in other arthritides. METHODS Scintigraphic scores were compared with the Ritchie index and biochemical variables of disease activity. RESULTS In RA, scintigraphic scores were reproducible and seemed to perform better than clinical scores. Moreover, the sco...

UNLABELLED One of the major limitations of gamma cameras is their relatively poor energy resolution. The main practical consequence of this is that the detection of both scattered and unscattered photons in the photopeak energy window, affecting image contrast and resolution, makes the data inconsistent with the assumption of scatter-free projection data in reconstruction and attenuation correc...

Rodent monitoring in biomedical laboratories is a time consuming and tedious task. Several automatic solutions that rely on different types of sensors have been proposed. Computer vision provides a significantly more universal and less intrusive solution. In this article we propose a new method to detect and classify three behaviors in rodents: Exploring, Rearing, and Static. The method uses Mo...