Background and objectives: Reducing postoperative pain in hemorrhoidectomy is still a challenge. This prospective, randomized, double-blind study was conducted to compare bilateral pudendal blockade with peripheral nerve stimulator to relieve postoperative pain with the method commonly used. Method: 200 patients scheduled for hemorrhoidectomy were randomly divided into Control Group and Pudenda...

BACKGROUND The supplementation of local anaesthetics with adjuvants to improve the efficacy of subarachnoid block has been recognised since long. The most preferred drug has been opioids, but newer drugs like dexmedetomidine has also been introduced and investigated as an effective adjuvant. AIM This study was conducted to evaluate and compare the characteristics of subarachnoid blockade, hem...

Background: Inguinal hernia repair is one of the most common surgical conditions. In absence other comorbidities, it can be performed as a day-care procedure. Spinal anesthesia preferred technique this surgery. Local anesthetics having rapid and smooth onset action, good intraoperative analgesia, short recovery period, least side effects are preferred. Aims Objectives: The objective study was t...

Background: Dexmedetomidine, a selective ?2 agonist has shown promising results when used as premedicant. This prospective randomized study evaluated the efficacy of two different premedication regimens in achieving smooth conduct anesthesia and optimum pain relief pediatric cataract surgeries. Methods: 90 ASA I or II children, aged 1-6 years, scheduled for elective surgeries were to receive ei...

melatonin has been suggested as a new natural pain killer in inflammatory pain and during surgical procedures. we designed this randomized double-blind controlled study to evaluate the analgesic efficacy and also optimal preemptive dose of melatonin in patients undergoing cesarean section under spinal anesthesia.one hundred twenty patients scheduled for cesarean section under spinal anesthesia ...

The aim of this study was to investigate the efficacy of postoperative scheduled intravenous acetaminophen to reduce the opioid use and enhance recovery after gastrectomy.Opioid use is reportedly associated with delayed recovery of gastrointestinal (GI) peristalsis and postoperative nausea/vomiting (PONV) despite of acceptable efficacy for pain control.Of 147 and 96 consecutive patients who und...

Breakthrough pain is a newly recognized pain category that was first described by Portenoy and Hagen in 1990. The term describes pain that increases in intensity to "break through" chronic pain that is being controlled by a scheduled opioid regimen. The development of fluctuations in pain intensity is challenging due to their unpredictable nature, rapid onset, and need for rapid treatment inter...

Abstract Background The aim of this study was to assess the effect addition 500-mg magnesium sulfate (MgSo 4 ) or 8-mg dexamethasone bupivacaine in bilateral ultrasound-guided quadratus lumborum block (QLB), on duration post-operative analgesia, patient’s hemodynamic parameters, severity pain, number patients who required rescue total dose pethidine given, maintained analgesia for 36 h, and tim...

Background: Caudal anaesthesia is the most common regional technique for regional anaesthesia in pediatrics. However, many adjuvants are now used to prolong its analgesic effect. In this study we investigate the addition of dexmedetomidine to bupivacaine in caudal analgesia for major abdominopelvic surgeries in pediatrics. Methods: Sixty children ASA I or II, males and females, aged 6 months to...